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Product Name | Paroxetine maleate |
Description | Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for α1-, α2- or β-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo. Purity 99%. MW (observed): 445.44 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine maleate |
Gene, Accession, CAS # | CAS: 64006-44-6 |
Catalog # | 2141/10 |
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Order / More Info | Paroxetine maleate from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19890001, 21422376, 23254343, 25056731, 25404050, 26441665 |
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