产品详情 |
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Product Name | Rotenone |
Description | Mitochondrial electron transport chain inhibitor (IC50 = 1.7 - 2.2 μM at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. May also inhibit autophagy induction; blocks lysosomal degradation of autophagic vacuoles. Cell-permeable and brain penetrant. Purity 95%. MW (observed): 394.42 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one |
Gene, Accession, CAS # | CAS: 83-79-4 |
Catalog # | 3616/50 |
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Order / More Info | Rotenone from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22948162, 25260615, 27323329, 27870947, 28700943 |
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