| 产品详情 |
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| Product Name | Rottlerin |
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| Description | Originally reported to inhibit PKC isoforms. Also reported to inhibit CAM kinase III. However, recently shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Also shown to act as a direct mitochondrial uncoupler. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways. MW (observed): 516.55. |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone |
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| Gene, Accession, CAS # | CAS: 82-08-6 |
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| Catalog # | 1610/50 |
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| Price | |
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| Order / More Info | Rottlerin from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20395409, 21593487, 23799098, 23995289, 24748172, 27111842 |
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| 产品资料 |
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