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Product Name | (R)-PFI 2 hydrochloride |
Description | Potent and selective SETD7 histone lysine methyltransferase inhibitor (IC50 = 2 nM). Exhibits >1000-fold selectivity over DNMT1 and a panel of 18 other methyltransferases. Inhibits YAP nuclear translocation and function following activation of the Hippo signaling pathway in MCF7 cells. Negative Control also available.. Purity 97%. MW (observed): 535.98 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl]1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride |
Gene, Accession, CAS # | CAS: 1627607-87-7 |
Catalog # | 4892/10 |
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Order / More Info | (R)-PFI 2 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25136132, 25897119, 29395054 |
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