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Product Name | (-)-[3R,4S]-Chromanol 293B |
Description | Enantiomer that selectively inhibits the slow component of delayed rectifier K+ current (IKs). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC50 values are 1.36 and 9.6 μM respectively). Has negligible inhibitory action at KV11.1 (hERG) channels (IC50 > 30 μM). Racemate also available.. Purity 99%. MW (observed): 324.39 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide |
Gene, Accession, CAS # | CAS: 163163-24-4 |
Catalog # | 1475/10 |
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Order / More Info | (-)-[3R,4S]-Chromanol 293B from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21890694, 22549510 |
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