产品详情 |
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Product Name | TC-I 15 |
Description | Potent α2β1 integrin inhibitor (IC50 values for the inhibition of human platelet adhesion to type I collagen are 12 and 715 nM for platelets under static conditions and under flow, respectively). Displays selectivity for α2β1 over αvβ3, α5β1, α6β1 and αIIbβ3 at concentrations exceeding 1000 nM. Reduces collagen IV production in mesangial cells. Active in vivo; prevents ferric chloride-induced clot formation in mice. Purity 98%. MW (observed): 520.62 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine |
Gene, Accession, CAS # | CAS: 916734-43-5 |
Catalog # | 4527/10 |
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Order / More Info | TC-I 15 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 29795344 |
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