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Product Name | TC KHNS 11 |
Description | Potent and selective PI 3-kinase δ inhibitor (biochemical IC50 values are 9, 262, 1650 and 4630 nM for PI 3-Kδ, PI 3-Kα, PI 3-Kβ and PI 3-Kγ, respectively; cellular IC50 values are 49, 3440 and 6530 nM for PI 3-Kδ, PI 3-Kα and PI 3-Kβ, respectively). Selective for PI 3-Kδ over a panel of lipid and protein kinases. Inhibits B-cell function. Exhibits moderate oral bioavailability in vivo. Purity 98%. MW (observed): 492.53 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-[4-[3-[(4-Acetyl-1-piperazinyl)carbonyl]phenyl]-6-quinazolinyl]-2-methoxy-3-pyridinecarbonitrile |
Gene, Accession, CAS # | CAS: 1431540-99-6 |
Catalog # | 6079/10 |
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Order / More Info | TC KHNS 11 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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