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Product Name | TCS 21311 |
Description | Potent JAK3 inhibitor (IC50 = 8 nM). Selective for JAK3 over JAK1, JAK2 and TYK2 (IC50 values are 1017, 2550 and 8055 nM respectively). Also inhibits GSK-3β, PKCα and PKCθ (IC50 values are 3, 13 and 68 nM respectively). Purity 98%. MW (observed): 526.51 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione. NIBR3049 |
Gene, Accession, CAS # | CAS: 1260181-14-3 |
Catalog # | 4221/10 |
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Order / More Info | TCS 21311 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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