| 产品详情 |
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| Product Name | XAV 939 |
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| Description | Potent tankyrase (TNKS) inhibitor (IC50 values are 4 and 11 nM for TNKS2 and TNKS1 respectively). Antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. Inhibits proliferation of the β-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells. Purity 98%. MW (observed): 312.31 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
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| Gene, Accession, CAS # | CAS: 284028-89-3 |
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| Catalog # | 3748/10 |
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| Price | |
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| Order / More Info | XAV 939 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21518928, 21706018, 22573687, 22907667, 23129487, 23924634, 24023784, 24052941, 24100450, 24684907, 25266063, 25568183, 25636740, 25680029, 25713298, 25865356, 25978043, 26076956, 26161513, 26357015, 26514269, 27906170, 28103884, 28536247, 28655839, 28943877, 29167563, 29281831, 29581478, 30573846 |
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