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| Product Name | XL 184 |
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| Description | Potent VEGFR inhibitor (IC50 = 0.035 nM); also inhibits c-Met, KIT, RET, FLT4, AXL, FLT3, FLT1 and Tie2 (IC50 values are 1.3, 4.6, 5.2, 6, 7, 11.3, 12 and 14.3 nM, respectively). Induces intratumoral hypoxia and apoptosis. Reduces tumor invasion and metastasis in vivo. Antiangiogenic. Purity 98%. MW (observed): 501.51 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide. Cabozantinib, BMS 907351 |
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| Gene, Accession, CAS # | CAS: 849217-68-1 |
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| Catalog # | 5422/10 |
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| Price | |
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| Order / More Info | XL 184 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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