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| Product Name | Y 11 |
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| Description | Potent inhibitor of focal adhesion kinase (FAK); prevents FAK autophosphorylation at the Y397 site (IC50 ~ 50 nM in an in vitro kinase assay). Displays selectivity for FAK over a panel of other kinases (concentration used in assay = 1 μM). Decreases cell viability in a number of cancer cell lines; blocks colony formation in SW620 and BT474 cell lines. MW (observed): 265.15. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(2-Hydroxyethyl)-3,5,7-triaza-1-azaniatricyclo[3.3.1.13,7]decane bromide |
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| Gene, Accession, CAS # | CAS: 1086639-59-9 |
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| Catalog # | 4498/10 |
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| Price | |
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| Order / More Info | Y 11 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25169943, 26630674 |
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