| 产品详情 |
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| Product Name | LY 341495 |
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| Description | Highly potent and selective group II metabotropic glutamate receptor antagonist (Ki/IC50 values are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGlu2, mGlu3, mGlu8, mGlu7a, mGlu1a, mGlu5a and mGlu4a receptors respectively). Readily brain penetrant and active in vivo. Disodium salt (Cat. No. 4062) also available. Also available as part of the Group II mGlu Receptor Tocriset™, Group III mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™. Purity 98%. MW (observed): 353.37 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid |
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| Gene, Accession, CAS # | CAS: 201943-63-7 |
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| Catalog # | 1209/50 |
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| Order / More Info | LY 341495 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 12486245, 12538871, 14608033, 15056716, 16339037, 16608916, 16624937, 16920620, 17521572, 17597589, 17684555, 17728701, 18003824, 18094230, 18195348, 18305255, 18614676, 18625258, 18945818, 19026992, 19255473, 19776267, 19821836, 20217053, 20237257, 20659148, 20860833, 21145007, 21147983, 21245210, 21628565, 21734298, 21945652, 22069494, 22123524, 22593048, 22634728, 22726616, 22896717, 23017017, 23047654, 23197707, 23378895, 23593498, 24559655, 24596089, 24985890, 24987341, 25180102, 25327839, 25505386, 25568131, 25673837, 25889381, 26274565, 26655894, 27385724, 27445731, 28135236, 28159646, 29213077, 29269878 |
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