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Product Name | LY 487379 hydrochloride |
Description | Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors. Promotes cognitive flexibility in a rat model. Purity 99%. MW (observed): 488.91 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2,2,2-Trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(3-pyridinylmethyl)ethanesulfonamide hydrochloride |
Gene, Accession, CAS # | CAS: 353229-59-1 |
Catalog # | 3283/50 |
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Order / More Info | LY 487379 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24381270, 25576798, 26496940, 29213077 |
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