| 产品详情 |
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| Product Name | PCNA I1 |
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| Description | Proliferating cell nuclear antigen (PCNA) inhibitor. Directly binds PCNA trimers (Kd = 0.41 μM), reduces chromatin-associated PCNA in cells, inhibits cell growth through induction of S and G2M arrest, and attenuates DNA replication in cells. Inhibits growth of a range of tumor cell lines in vitro with IC50 values in the nanomolar to low micromolar range. Inhibits growth of prostate tumor xenografts in mice. Purity 98%. MW (observed): 310.37 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-Methylthiophene-2-carboxylic acid)-N'-[(1-hydroxy-2-naphthalenyl)methylene]hydrazide |
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| Gene, Accession, CAS # | CAS: 444930-42-1 |
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| Catalog # | 5419/50 |
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| Price | |
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| Order / More Info | PCNA I1 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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