产品详情 |
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Product Name | PD 158780 |
Description | Potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively) that does not inhibit FGF or PDGF-mediated tyrosine phosphorylation. Induces G1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells. Purity 99%. MW (observed): 330.18 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
Gene, Accession, CAS # | CAS: 171179-06-9 |
Catalog # | 2615/10 |
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Order / More Info | PD 158780 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 27852438 |
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