产品详情 |
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Product Name | PD 146176 |
Description | Specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM) that has no demonstrable effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC50 = 0.54 μM for 15-LOX in rabbit reticulocytes). Lacks non-specific antioxidant properties and prevents atherogenesis via regulation of monocyte-macrophage enrichment in vivo. Purity 98%. MW (observed): 237.32 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole |
Gene, Accession, CAS # | CAS: 4079-26-9 |
Catalog # | 2850/50 |
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Order / More Info | PD 146176 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 15967159, 22633978 |
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