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Product Name | Aminopurvalanol A |
Description | Cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 20 - 35 nM for cdk1, cdk2 and cdk5). Also inhibits ERK1 (IC50 = 12.0 μM) and ERK2 (IC50 = 3.1 μM) and is 3000-fold selective over a range of other protein kinases (IC50 >100 μM). Arrests cell cycle at G2/M boundary (IC50 = 1.25 μM), and induces apoptosis at concentrations >10 μM. Cell permeable. Purity 98%. MW (observed): 403.91 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2R)-2-[[6-[(3-Amino-5-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol. NG 97 |
Gene, Accession, CAS # | CAS: 220792-57-4 |
Catalog # | 2072/10 |
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Order / More Info | Aminopurvalanol A from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 16309665 |
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