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| Product Name | Amlexanox |
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| Description | Selective inhibitor of TANK-binding kinase 1 (TBK1) and IKKε (IC50 values are ~1-2 μM). Displays no effect on IKKα or IKKβ at these concentrations. Reversibly lowers weight, increases insulin sensitivity, and reduces inflammation and steatosis in three mouse models of obesity. Exhibits antiallergic activity; inhibits the release of histamine from rat mast cells. Also binds to Hsp90 and inhibits C-terminal chaperone activity in vitro. Purity 99%. MW (observed): 298.29 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid |
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| Gene, Accession, CAS # | CAS: 68302-57-8 |
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| Catalog # | 4857/10 |
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| Price | |
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| Order / More Info | Amlexanox from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26012578 |
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