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| Product Name | AMN 082 dihydrochloride |
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| Description | The first selective mGlu7 agonist. Potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μM. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats. View important information regarding the usage of AMN 082 dihydrochloride . Purity 99%. MW (observed): 465.45 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N'-Bis(diphenylmethyl)-1,2-ethanediamine dihydrochloride |
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| Gene, Accession, CAS # | CAS: 97075-46-2 |
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| Catalog # | 2385/10 |
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| Order / More Info | AMN 082 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21627638, 30170084 |
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| 产品资料 |
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