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Product Name | EHT 1864 |
Description | Inhibitor of Rac family GTPases. Blocks activation by direct binding to Rac1, Rac1b, Rac2 and Rac3 (KD values are 40, 50, 60 and 250 nM respectively). Inhibits Rac, Ras and Tiam-induced growth transformation of NIH-3T3 fibroblasts. Reduces β-amyloid peptide production in vivo. Purity 98%. MW (observed): 581.47 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride |
Gene, Accession, CAS # | CAS: 754240-09-0 |
Catalog # | 3872/50 |
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Order / More Info | EHT 1864 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21622527, 22278715, 22689141, 23460186, 23486971, 23686855, 24025335, 25284585, 25631101, 25659579, 25915582, 26867574, 27503856, 28676702 |
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