产品详情 |
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Product Name | Perifosine |
Description | PKB/Akt inhibitor; accumulates in and reorganizes lipid rafts disrupting Akt signaling. Also inhibits MAPK pathway and induces autophagy. Induces apoptosis in leukemia cell lines. Decreases Kv2.1 current amplitude by modulating its inactivation gating. Antitumor. Orally bioavailable. Purity 99%. MW (observed): 461.66 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate. KRX-0401 |
Gene, Accession, CAS # | CAS: 157716-52-4 |
Catalog # | 6087/10 |
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Order / More Info | Perifosine from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19920197 |
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