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| Product Name | PF 06281355 |
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| Description | Selective myeloperoxidase (MPO) inhibitor (IC50 = 1.5 μM in LPS-stimulated human whole blood). Selective for MPO over a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. Inhibits MPO activity in peritoneal lavage and plasma in a murine peritonitis model. Also reduces lung edema in a murine pulmonary immune complex vasculitis model. Orally bioavailable. Purity 98%. MW (observed): 321.35 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide |
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| Gene, Accession, CAS # | CAS: 1435467-38-1 |
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| Catalog # | 6004/10 |
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| Price | |
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| Order / More Info | PF 06281355 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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