| 产品详情 |
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| Product Name | MS 275 |
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| Description | Class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively). Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo. Increases estrogen receptor α- and aromatase expression in breast cancer cells. Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter. Purity 99%. MW (observed): 376.41 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate. entinostat, SNDX 275 |
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| Gene, Accession, CAS # | CAS: 209783-80-2 |
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| Catalog # | 6208/10 |
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| Price | |
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| Order / More Info | MS 275 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 29695769 |
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| 产品资料 |
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