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| Product Name | MS 436 |
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| Description | Potent and selective BRD4 bromodomain inhibitor (Ki = 30 - 50 nM for the first bromodomain (BRD4(1)). Exhibits 10-fold selectivity for BRD4(1) over BRD4(2). Blocks BRD4 transcriptional activity in lipopolysaccharide-induced production of both nitric oxide and IL-6 in mouse macrophages (IC50 values are 3.8 and 4.9 μM, respectively). Attenuates melanoma cell proliferation in vitro. Purity 98%. MW (observed): 383.42 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 1395084-25-9 |
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| Catalog # | 5173/10 |
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| Price | |
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| Order / More Info | MS 436 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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