产品详情 |
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Product Name | Tetrabenazine |
Description | Potent inhibitor of vesicular monoamine uptake; depletes stores of dopamine, serotonin and noradrenalin. Binds with high affinity (IC50= 3.2 nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors. Causes behavioral depression; inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice. Deuterated analog also available.. Purity 98%. MW (observed): 317.2 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one |
Gene, Accession, CAS # | CAS: 58-46-8 |
Catalog # | 2175/50 |
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Order / More Info | Tetrabenazine from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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