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Product Name | GMDS, 1-372aa, Human, His tag, E.coli |
Description | Purity: > 95% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF. GMDS, also known as SDR3E1, belongs to the GDP-mannose 4,6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. Recombinant human GMDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | GDP-mannose 46 dehydratase, GDP-mannose 4,6 dehydratase, GMD, SDR3E1 |
Gene, Accession, CAS # | NP 001491 |
Catalog # | ATGP1282 |
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Order / More Info | GMDS, 1-372aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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