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| Product Name | PAD4 Autoantibody ELISA Kit |
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| Description | PAD4 is a guanidino-modifying enzyme which catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. PAD4 activity is increased in rheumatoid arthritis (RA), producing citrulline-containing proteins (CCP) that induce the formation of arthritogenic autoantibodies. In addition to anti-CCP autoantibodies, 23-45% of RA patients also produce autoantibodies specific for the PAD4 enzyme itself. Cayman's PAD4 Autoantibody ELISA Kit is an immunometric assay which can be used to measure anti-PAD4 autoantibodies of any isotype (IgM, IgG, and IgA) in human plasma and serum without prior sample purification. Affinity-purified anti-PAD4 antibody isolated from the plasma of a patient with RA is used as the standard. One unit is approximately equal to 1 ng of anti-PAD4 Ig protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 31.3 U/ml. |
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| Size | 96 well |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | PAD4 Autoantibody EIA Kit|PADI4|PADI5|PDI5|Peptidylartginine Deaminase 4|Protein Arginine Deiminase 4 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 500930-96WELLS |
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| Order / More Info | PAD4 Autoantibody ELISA Kit from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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