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Product Name | NKH 477 |
Description | Water-soluble analog of forskolin (Cat. No. 1099) that is a potent activator of adenylyl cyclase; shows some selectivity for cardiac (type V) adenylyl cyclase. Stimulates bronchodilation (EC50 = 32.6 nM) and is an orally active potent positive chronotrope and hypotensive agent in vivo. Also available as part of the PKA Tocriset™. Purity 98%. MW (observed): 546.1 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride. Colforsin dapropate hydrochloride, 6-(3-dimethylaminopropionyl)forskolin hydrochloride |
Gene, Accession, CAS # | CAS: 138605-00-2 |
Catalog # | 1603/10 |
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Order / More Info | NKH 477 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21598037, 22713909, 23143333, 23571017, 26431344, 27270401, 28368420 |
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