| 产品详情 |
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| Antigenic Specificity | KLRK1 / CD314 / NKG2D |
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| Clone | 1D11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:50 - 1:200), Func, IHC, IHC-Fr, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KLRK1 / CD314 / NKG2D Antibody (clone 1D11, Low Endotoxin) LS-C44804. Specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6). |
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| Immunogen | NKL cells. |
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| Other Names | KLRK1, D12S2489E, CD314 antigen, KLR, NK cell receptor D, NKG2D, NKG2-D, NKG2-D-activating NK receptor, CD314 |
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| Gene, Accession # | KLRK1, Gene ID: 22914 |
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| Catalog # | LS-C44804 |
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| Price | |
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| Order / More Info | KLRK1 / CD314 / NKG2D Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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