| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | KLRK1 / CD314 / NKG2D |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | KLRK1 / CD314 / NKG2D Antibody (FITC) LS-C499205. Specificity: Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. |
|---|
| Immunogen | Recombinant Human NKG2-D type II integral membrane protein (73-216AA) |
|---|
| Other Names | KLRK1, D12S2489E, CD314 antigen, KLR, NK cell receptor D, NKG2D, NKG2-D, NKG2-D-activating NK receptor, CD314 |
|---|
| Gene, Accession # | KLRK1, Gene ID: 22914 |
|---|
| Catalog # | LS-C499205 |
|---|
| Price | |
|---|
| Order / More Info | KLRK1 / CD314 / NKG2D Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|