产品详情 |
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Antigenic Specificity | Lamin A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.2 mg/ml |
Applications | Western blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lamin A Antibody. Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication and chromatin organization. Lamin A is specifically cleaved by caspase-6 and therefore serves as a marker for caspase-6 activation. During apoptosis the 70 kDa lamin A is cleaved to a large (40-45 kDa) and small (23 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death. |
Immunogen | Synthetic peptide surrounding amino acid 220 of human Lamin A |
Other Names | LMNA, HGPS, EMD2, FPLD, CDCD1, LDP1, LGMD1B, IDC, Lamin-A/C, CDDC ,LMN1 , CMD1A, PRO1 |
Gene, Accession # | Gene ID: 4000, Accession: BC033088 |
Catalog # | 3267-100 |
Price | |
Order / More Info | Lamin A Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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