| 产品详情 |
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| Product Name | 2-(Phosphonomethyl)-pentanedioic Acid |
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| Description | A potent inhibitor of GCP II/NAALADase (Ki = 98 pM for release of glutamate from the NAALADase peptide substrate NAAG); selective for GCP II/NAALADase over a panel of 100 receptors, transporters, ion channels, and enzymes at a concentration of 10 µM; neuroprotective against hypoxia (EC50 = 8.4 µM) in neuron-enriched primary cultures from rat embryo cerebellum; reduces neuronal cell death induced by middle cerebral artery occlusion in rats; blocks the conditioned place preference response to cocaine in male rats (100 mg/kg); reduces the number of flinches induced by formalin injection into the footpad of mice (10 µg per animal); decreases severity and delays onset of EAE in mice, |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-PMPA |
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| Gene, Accession, CAS # | CAS: 173039-10-6 |
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| Catalog # | 21916-1 |
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| Price | |
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| Order / More Info | 2-(Phosphonomethyl)-pentanedioic Acid from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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