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| Product Name | Human CD95 (APO-1/Fas) Recombinant Protein |
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| Description | Human CD95 (APO-1/Fas) Recombinant Protein, eBioscience™. CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses. |
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| Size | 50 µg |
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| Concentration | lyophilized |
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| Applications | Control: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 355; Uniprot: P25445 |
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| Catalog # | BMS314 |
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| Order / More Info | Human CD95 (APO-1/Fas) Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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