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| Product Name | Human TNF alpha Recombinant Protein |
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| Description | Human TNF alpha Recombinant Protein. TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions |
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| Size | 50 µg |
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| Concentration | lyophilized |
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| Applications | Control: Assay Dependent |
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| Other Names | Tumor necrosis factor alpha |
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| Gene, Accession, CAS # | Entrez: 7124; Uniprot: P01375 |
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| Catalog # | RP-10921 |
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| Order / More Info | Human TNF alpha Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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