产品详情 |
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Antigenic Specificity | APC |
Clone | Ali 12-28 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | peroxidase (HRP) conjugate |
Size | 50 ul |
Concentration | n/a |
Applications | ELISA, IHC-Fr, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to APC (HRP). This antibody recognises adenomatous polyposis coli (APC), a 310kDa protein that functions as a tumour suppressor. APC tumour suppressor gene is mutated in the inherited disease familial adenomatous polyposis (FAP) and in over 80% of colorectal cancers. The antibody Ali 12-28 recognises a region corresponding to nucleotides 135 and 422 of the APC (exons 2-3) in the N-terminus. It detects both normal and mutant-truncated forms of the APC and may be used for the detection of APC expression and APC mutations. |
Immunogen | N-terminal APC-MBP fusion protein |
Other Names | adenomatosis polyposis coli tumor suppressor, adenomatous polyposis coli, Adenomatous polyposis coli protein, APC, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, DP3, GS, Protein APC |
Gene, Accession # | Gene ID: 324, UniProt: P25054 (Human) |
Catalog # | orb223644 |
Price | |
Order / More Info | APC Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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