| 产品详情 |
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| Antigenic Specificity | APC |
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| Clone | Ali 12-28 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | 0.1 ml |
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| Concentration | n/a |
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| Applications | ELISA, FACS, ICC, IF, IHC-Fr, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse monoclonal to APC. This antibody recognises adenomatous polyposis coli (APC), a 310kDa protein that functions as a tumour suppressor. APC tumour suppressor gene is mutated in the inherited disease familial adenomatous polyposis (FAP) and in over 80% of colorectal cancers. The antibody Ali 12-28 recognises a region corresponding to nucleotides 135 and 422 of the APC (exons 2-3) in the N-terminus. It detects both normal and mutant-truncated forms of the APC and may be used for the detection of APC expression and APC mutations. |
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| Immunogen | N-terminal APC-MBP fusion protein |
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| Other Names | adenomatosis polyposis coli tumor suppressor, adenomatous polyposis coli, Adenomatous polyposis coli protein, APC, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, DP3, GS, Protein APC |
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| Gene, Accession # | Gene ID: 324, UniProt: P25054 (Human) |
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| Catalog # | orb223642 |
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| Price | |
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| Order / More Info | APC Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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