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Product Name | Limaprost |
Description | Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro. Intra coronary injection (100 ng/kg) or intravenous injection (3 µg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 µg/kg orally in rats.{6808} |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 17α,20-dimethyl-Δ2-PGE1|17α,20-dimethyl-Δ2-Prostaglandin E1 |
Gene, Accession, CAS # | CAS: 74397-12-9 |
Catalog # | 13810-5 |
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Order / More Info | Limaprost from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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