产品详情 |
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Antigenic Specificity | p21Cip1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 400 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to p21Cip1. May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). |
Immunogen | This Mouse p21Cip1 Antibody Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-159 amino acids from the C-term region of mouse p21Cip1. |
Other Names | Cdkn1a, Cip1, Waf1, Cyclin-dependent kinase inhibitor 1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Cyclin-dependent kinase inhibitor 1, Melanoma differentiation-associated protein, Cyclin-dependent kinase inhibitor 1, p21 |
Gene, Accession # | n/a |
Catalog # | orb107018 |
Price | |
Order / More Info | p21Cip1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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