细胞牵张力共培养系统，flexercell transwell holder，细胞牵张共培养系统，细胞牵拉共培养系统
型号:FX-5000T
联系人:李先生
联系电话:18618101725
品牌:flexercell
FX-5000T细胞牵张拉伸应力加载系统(flexercell FX5000 Tension system)
亮点：
1）该系统对二维、三维细胞和组织各种培养物提供轴向和圆周应力加载；不但具有双轴向拉伸力加载，还具备单轴向加力功能
2）计算机控制的应力加载系统，为体外培育的细胞提供j确的、可控制的、可重复的、静态的或者周期性的应力变化。
3）使用真空泵，抻拉培养板底部的弹性硅胶模，细胞培养板底部高伸展度可达到33%，通过气体装置可以自动调节和控制应力。
4）基于柔性膜基底变形、受力均匀;
5）可实时观察细胞、组织在应力作用下的反应;
6）具的flexstop隔离阀可使同一块培养板力的一部分培养孔的细胞受力，一部分培养孔的细胞不受力，方便对比实验;
7）与压力传导仪整合，同时兼备多通道细胞压力加载功能;
8）与Flex Flow平行板流室配套，可在牵拉细胞的同时施加流体切应力;
9）多达4通道，可4个不同程序同时运行，进行多个不同拉伸形变率对比实验；
10）同一程序中可以运行多种频率，多种振幅和多种波形；
11）加载模拟波形种类丰富：静态波形、正旋波形、心动波形、三角波形、矩形以及各种te制波形；
12）更好地控制在超低或超高应力下的波形；
13)电脑系统对牵张拉伸力加载周期、大小、频率、持续时间j确智能调控
14)加载分析各种细胞在牵张拉应力刺激下的生物化学反应
15)伸展度范围广：0-33%
16)牵拉频率范围广：0.01-5Hz
17)可以在6孔板和24孔牵张拉伸培养板实现不同细胞系的共培养
flexercell® Transwell Holder 图
图 1
Holders sit atop a 6-well or a 24-well flexercell® Culture Plate (图 1) and allow users to run co-culture or cell migration assays with standard transwells.
- Analyze cell migration in response to strain.
- Run experiments with unstrained control cells and the strained cells in the same culture plate well.
- Compatible with Transwells for 6-well* and 24-well** plates.
*6-well inserts with a 24 mm insert diameter or with a 37-41 mm outer lip diameter and 15.5-16.5 mm height.
**24-well inserts with a 6.5 mm insert diameter or with a 16.9-18.8 mm outer lip diameter and 15.5-16.5 mm height.
Applications of Transwell® with flexercell® Culture Plates
- Co-Culture - Culture two different cell types in the presence or absence of mechanical load. Isolate direct and auto/paracrine effects of mechanical load.
- Cell Migration - Examine the paracrine/autocrine effects of substrate strain on cell migration.
- Transport & Permeability - Examine drug transport in response to the paracrine effects of mechanical load.
- Cell Polarity - Analyze the formation of polarized layers of cells in response to the paracrine effects brought about by mechanical load. In addition, examine epithelial penetration by pathogens, wound repair, ion channel activity, and other processes that rely on well-differentiated polarized cell layers.
- Chemotaxis & Invasion - Analyze the effects of mechanical load on inflammatory cell migration, metastatic invasion, and angiogenesis.
 Figure 1: Schematic of a Transwell Holder with a Transwell supported atop the rubber membrane in the well of BioFlex® culture plate. |
