磁镊系统，生物单分子操纵磁镊，单分子磁镊子，单分子操纵磁镊装置，单分子拉伸和扭转磁镊
型号:单分子磁镊
联系人:李先生
联系电话:18618101725
品牌:法国
磁镊系统，生物单分子操纵磁镊，单分子磁镊子，单分子操纵磁镊装置，单分子拉伸和扭转磁镊
该磁镊装置基于专用倒置显微镜，安装在电动平移和旋转平台上，其原理是通过梯度分布的磁场对处于其中可磁化小珠施力观察并分析其运动。使用一对强大的稀土磁铁(BdFeB)来使磁珠磁化强度能够达到饱和值。高精度温度控制装置、te殊的样品固定装置、保证磁珠快速旋转的步进电机和灵活管理的计算机软件系统及万像素的CCD相机，可同时实现多达40个单个分子的视频采集和跟踪测量，提单分子高通量分析和统计水平。
系统亮点概述
（1）稳定健壮—PicoTwist单分子操纵磁镊装置具有非常低的图像漂移设计
（2）高分辨率、力的范围广—具有非常薄的样品固定装置
（3）配备磁珠跟踪软件，可实时进行数据分析
（4）高通量，可以同时实现多达40个单个分子的视频采集和跟踪测量，大大提单分子的高通量分析和统计水平
Bibliography |
|
| Limit | Field type |
| Single Molecule BiophysicsSingle molecule ConductivityTheoryOptical TweezersMagnetic TweezersBiomembrane Force ProbeMicro PipetteAtomic Force MicroscopySimple Tethered particleFluorescence Resonance Energy TransferFluorescence Correlation SpectroscopyTwo Photons exitationTotal Iternal ReflectionNano-CrystalEpifluorescencePolymer elasticityEnzymatic activityDNA molecular motorMolecular motorOther shortwith abstractall info | |
| Edit 0 |
Mechanically controlled DNA extrusion from a palindromic sequence by single molecule micromanipulation A. Dawid, F. Guillemot, C. Breme, V. Croquette, F. Heslot, Phys. Rev. Lett. (2006) 96-18 p. PubMed |
| Edit 1 |
Direct observation of DNA distortion by the RSC complex G. Lia, E. Praly, HA. Ferreira, C. Stockdale, YC. Tse-dinh, D. Dunlap, V. Croquette, D. Bensimon, T. Owen-hughes, Mol. Cell (2006) 21-3 p.417 PubMed |
| Edit 2 |
Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I R. Seidel, JGP. Bloom, J. Van Noort, CF. Dutta, NH. Dekker, K. Firman, MD. Szczelkun, C. Dekker, Embo J. (2005) 24-23 p.4188 PubMed |
| Edit 3 |
Statistical determination of the step size of molecular motors KC. Neuman, OA. Saleh, T. Lionnet, G. Lia, JF. Allemand, D. Bensimon, V. Croquette, J. Phys.-Condes. Matter (2005) 17-47 p.S3811 PubMed |
| Edit 4 |
Topoisomerase IV bends and overtwists DNA upon binding G. Charvin, TR. Strick, D. Bensimon, V. Croquette, Biophys. J. (2005) 89-1 p.384 Biophyscal publications |
| Edit 5 |
Biocompatible force sensor with optical readout and dimensions of 6 nm(3) H. Shroff, BM. Reinhard, M. Siu, H. Agarwal, A. Spakowitz, J. Liphardt, Nano Lett. (2005) 5-7 p.1509 PubMed |
| Edit 6 |
Braiding DNA: Experiments, simulations, and models G. Charvin, A. Vologodskii, D. Bensimon, V. Croquette, Biophys. J. (2005) 88-6 p.4124 Biophyscal publications |
| Edit 7 |
Single-molecule manipulation measurements of DNA transport proteins OA. Saleh, JF. Allemand, V. Croquette, D. Bensimon, ChemPhysChem (2005) 6-5 p.813 PubMed |
| Edit 8 |
Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB DA. Koster, V. Croquette, C. Dekker, S. Shuman, NH. Dekker, Nature (2005) 434-7033 p.671 PubMed |
| Edit 9 |
Single-molecule DNA nanomanipulation: Improved resolution through use of shorter DNA fragments A. Revyakin, RH. Ebright, TR. Strick, Nat. Methods (2005) 2-2 p.127 PubMed |
| Edit 10 |
Single-molecule study of DNA unlinking by topoisomerase IV: Influence of the crossing angle. KC. Neuman, G. Charvin, D. Bensimon, V. Croquette, Biophys. J. (2005) 88-1 p.15A Biophyscal publications |
| Edit 11 |
Single molecule investigations of the mechanochemical cycle of DNA gyrase J. Gore, MD. Stone, Z. Bryant, NJ. Crisona, S. Mitelheiser, A. Maxwell, NR. Cozzarelli, C. Bustamante, Biophys. J. (2005) 88-1 p.184A Biophyscal publications |
| Edit 12 |
Topoisomerase 1B: its mechanism and interactions with spinning DNA studied at the single molecule level D. Koster, S. Shuman, C. Dekker, NH. Dekker, Biophys. J. (2005) 88-1 p.381A Biophyscal publications |
| Edit 13 |
Single-molecule measurements of the persistence length of double-stranded RNA JA. Abels, F. Moreno-herrero, T. Van Der Heijden, PTM. Veenhuizen, MM. Bruinink, C. Dekker, NH. Dekker, Biophys. J. (2005) 88-1 p.570A Biophyscal publications |
| Edit 14 |
Human Rad51 filaments on double- and single-stranded DNA: correlating regular and irregular forms with recombination function D. Ristic, M. Modesti, T. Van Der Heijden, J. Van Noort, C. Dekker, R. Kanaar, C. Wyman, Nucleic Acids Res. (2005) 33-10 p.3292 PubMed |
| Edit 15 |
Extracting DNA twist rigidity from experimental supercoiling data S. Neukirch, Phys. Rev. Lett. (2004) 93-19 p. PubMed |
| Edit 16 |
Micromechanical analysis of the binding of DNA-bending proteins HMGB1, NHP6A, and HU reveals their ability to form highly stable DNA-protein complexes D. Skoko, B. Wong, RC. Johnson, JF. Marko, Biochemistry (2004) 43-43 p.13867 PubMed |
| Edit 17 |
Electromagnetic needles with submicron pole tip radii for nanomanipulation of biomolecules and living cells BD. Matthews, DA. Lavan, DR. Overby, J. Karavitis, DE. Ingber, Appl. Phys. Lett. (2004) 85-14 p.2968 PubMed |
| Edit 18 |
Studies on biomolecules using single molecule imaging and manipulation techniques Y. Harada, Sci. Technol. Adv. Mater. (2004) 5-5-6 p.709 PubMed |