激光散斑血流成像系统

 -视网膜血流变化实时观察装置

激光散斑血流成像系统，是基于激光散斑对比分析技术，可对大面积组织进行实时的血流动态成像监测，可用于人和动物观察血管的血流分布和变化的实际需求；为血流灌注和微循环研究提供了quan新方法。

与传统的激光多普勒成像技术相比，激光散斑对比分析技术的空间分辨率高，采样速度超快，

不仅可为待测组织提供动态血流监测曲线和彩色图像，而且还能提供实时quan区域血流视频数据结果，数据结果更为丰富和quan面

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Department of Ophthalmology, Hokkaido University

1. Hirose S, Saito W, Yoshida K, Saito M, Dong Z, Namba K, Satoh H, Ohno S.
   Elevated choroidal blood flow velocity during systemic corticosteroidtherapy in Vogt-Koyanagi-Harada disease
   Acta Ophthalmol. 2008 Dec;86(8):902-7. Epub 2008 Nov 12.
2. Michiyuki Saito, Kazuhiko Yoshida, Wataru Saito, Akio Fujiya, Kazuhiro Ohgami, Nobuyoshi Kitaichi, Hiroki Tsukahara, Susumu Ishida and Shigeaki Ohno
   Astaxanthin increases choroidal blood flow velocity
   Graefe's Archive for Clinical and Experimental Ophthalmology ,Vol.250, No.2, 239-245, DOI: 10.1007/s00417-011-1843-1, 2012.
3. Hashimoto Y, Saito W, Mori S, Saito M, Ishida S
   Increased macular choroidal blood flow velocity during systemic corticosteroid therapy in a patient with acute macular neuroretinopathy
   Clinical Ophthalmology, 2012:6, 1645-1649
4. Michiyuki Saito, Wataru Saito, Yuki Hashimoto, Chikako Yoshizawa, Akio Fujiya, Kousuke Noda, Susumu Ishida
   Macular choroidal blood flow velocity decreases with regression of acute central serous chorioretinopathy
   Br J Ophthalmol doi:10.1136/bjophthalmol-2012-302349
5. Michiyuki Saito, Wataru Saito, Yuki Hashimoto, Chikako Yoshizawa, Yasuhiro Shinmei, Kousuke Noda, Susumu Ishida
   Correlation between decreased choroidal blood flow velocity and the pathogenesis of acute zonal occult outer retinopathy
   Clinical and Experimental Ophthalmology, DOI:10.1111/ceo.12143
6. Ai Takahashi, Wataru Saito, Yuki Hashimoto, Michiyuki Saito, Susumu Ishida
   Impaired Circulation in the Thickened Choroid of a Patient with Serpiginous Choroids
   Ocular Immunology and Inflammation, Posted online on April 11, 2014. doi:10.3109/09273948.2014.902075
7. Kiriko Hirooka, Wataru Saito, Kousuke Noda and Susumu Ishida
   Enhanced-depth Imaging Optical Coherence Tomography and Laser Speckle Flowgraphy in a Patient with Acute Macular Neuroretinopathy
   Ocular Immunology & Inflammation, (0), 1-5, 2014. doi:10.3109/09273948.2014.916305
8. Kiriko Hirooka, Wataru Saito, Yuki Hashimoto, Michiyuki Saito and Susumu Ishida
   Increased macular choroidal blood flow velocity and decreased choroidal thickness with regression of punctate inner choroidopathy
   BMC Ophthalmology, 14(1), 73, 2014.
9. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Kiriko Hirooka, Shohei Mori, Kousuke Noda and Susumu Ishida
   Decreased choroidal blood flow velocity in the pathogenesis of multiple evanescent white dot syndrome
   Graefe's Archive for Clinical and Experimental Ophthalmology, 2014, 1-8.
10. Kiriko Hirooka, Wataru Saito, Kenichi Namba, Yuko Takemoto, Kazuomi Mizuuchi, Tomoe Uno, Yoshiaki Tagawa, Yuki Hashimoto and Susumu Ishida
    Relationship between choroidal blood flow velocity and choroidal thickness during systemic corticosteroid therapy for Vogt–Koyanagi–Harada disease
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2015, 1-9.
11. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Kiriko Hirooka, Shohei Mori, Kousuke Noda and Susumu Ishida
    Increased choroidal blood flow velocity with regression of unilateral acute idiopathic maculopathy
    Japanese Journal of Ophthalmology, 2015, 1-9.
12. Michiyuki Saito, Wataru Saito, Kiriko Hirooka, Yuki Hashimoto, Shohei Mori, Kousuke Noda and Susumu Ishida
    Pulse Waveform Changes in Macular Choroidal Hemodynamics With Regression of Acute Central Serous Chorioretinopathy
    Investigative Ophthalmology & Visual Science, 56(11), 6515-6522, 2015.
13. Kiriko Hirooka, Wataru Saito , Michiyuki Saito, Yuki Hashimoto, Shohei Mori, Kousuke Noda and Susumu Ishida
    Increased choroidal blood flow velocity with regression of acute posterior multifocal placoid pigment epitheliopathy
    Japanese Journal of Ophthalmology, 2016, 1-7.
14. Yuko Takemoto, Kenichi Namba, Kazuomi Mizuuchi, Daiju Iwata, Tomoe Uno, Shigeaki Ohno, Kiriko Hirooka, Yuki Hashimoto, Wataru Saito, Kazuhisa Sugiyama and Susumu Ishida
    Choroidal circulation impairment during the anterior recurrence of Vogt–Koyanagi–Harada disease confirmed with indocyanine green angiography and laser speckle flowgraphy
    Acta Ophthalmologica, 2016.
15. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Yuka Hasegawa, Akari Takita, Shohei Mori, Kousuke Noda and Susumu Ishida
    Relationship between Choroidal Thickness and Visual Field Impairment in Acute Zonal Occult Outer Retinopathy
    Journal of Ophthalmology, 2017.
16. Michiyuki Saito, Kousuke Noda, Wataru Saito and Susumu Ishida
    Relationship between choroidal blood flow velocity and choroidal thickness in patients with regression of acute central serous chorioretinopathy
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s0041, 2017.
17. Akari Takita, Yuki Hashimoto, Wataru Saito, Satoru Kase and Susumu Ishida
    Changes in blood flow velocity and thickness of the choroid in a patient with leukemic retinopathy
    American journal of ophthalmology case reports, doi:10.1016/j.ajoc.2018.09.001, 2018.
18. Iku Kikuchi, Satoru Kase, Yuki Hashimoto, Kiriko Hirooka and Susumu Ishida
    Involvement of circulatory disturbance in optic disk melanocytoma with visual dysfunction
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-019-04257-7, 2019.
19. Yuki Hashimoto, Wataru Saito, Michiyuki Saito, Yuka Hasegawa and Susumu Ishida
    Increased thickness and decreased blood flow velocity of the choroid in a patient with acute macular neuroretinopathy
    BMC Ophthalmology, 19:109, doi:10.1186/s12886-019-1123-0, 2019.
20. Wataru Saito, Susumu Ishida
    Acute Zonal Occult Outer Retinopathy
    Inflammatory and Infectious Ocular Disorders. Retina Atlas., doi:10.1007/978-981-13-8546-9_6, 2019.
21. Michiyuki Saito, Kousuke Noda, Wataru Saito, Kiriko Hirooka, Yuki Hashimoto and Susumu Ishida
    Increased choroidal blood flow and choroidal thickness in patients with hypertensive chorioretinopathy
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-019-04511-y, 2019.
22. Yuka Hasegawa, Yuki Hashimoto, Yasuhiro Shinmei and Susumu Ishida
    Optic nerve head microcirculation in congenital nasal optic disc hypoplasia
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-019-04540-7, 2019.
23. Wataru Saito, Yuki Hashimoto, Kiriko Hirooka and Susumu Ishida
    Changes in choroidal blood flow velocity in patients diagnosed with central serous chorioretinopathy during follow-up for pachychoroid pigment epitheliopathy
    American Journal of Ophthalmology Case Reports, doi:10.1016/j.ajoc.2020.100651, 2020.
24. Mizuho Mitamura, Satoru Kase and Susumu Ishida
    Multimodal imaging in sclerochoroidal calcification: a case report and literature review
    BMC Ophthalmology, 5(1), 1-5, doi:10.1186/s12886-020-01520-y, 2020.
25. Mizuho Mitamura, Satoru Kase, Kiriko Hirooka and Susumu Ishida
    Laser speckle flowgraphy in juxtapapillary retinal capillary hemangioblastoma: a case report on natural course and therapeutic effect
    Oncotarget, 11(42), 3800-3804, doi:10.18632/oncotarget.27771, 2020.
26. Satoru Kase, Hiroaki Endo, Mitsuo Takahashi, Masahiko Yokoi, Yuki Ito, Satoshi Katsuta, Shozo Sonoda, Taiji Sakamoto, Susumu Ishida and Manabu Kase
    Involvements of choroidal vascular structures with local treatments in patients with diabetic macular edema
    European Journal of Ophthalmology, doi:10.1177/11206721211027103, 2021.
27. Yui Yamashita, Michiyuki Saito, Kiriko Hirooka and Susumu Ishida
    Laser speckle flowgraphy findings in focal scleral nodule
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-021-05391-x, 2021.
28. Kiriko Hirooka, Michiyuki Saito, Yui Yamashita, Yuki Hashimoto, Nobuhiro Terao, Hideki Koizumi, Kousuke Noda and Susumu Ishida
    Imbalanced choroidal circulation in eyes with asymmetric dilated vortex vein
    Japanese Journal of Ophthalmology, 66(1), 14-18, doi:10.1007/s10384-021-00889-7, 2021.
29. Satoru Kase, Ayaka Hasegawa, Kiriko Hirooka, Hiroaki Endo, Kousuke Noda and Susumu Ishida
    Laser speckle flowgraphy findings in a patient with radiation retinopathy
    International Journal of Ophthalmology, 15(1), 172-174, doi:10.18240/ijo.2022.01.26, 2022.

Department of Ophthalmology, Sapporo Medical University

1. H.Tagawa, H. Furukawa and H. Fujii
   Effect of topical timolol on the blood velocity of the iris microcirculation and the aqueous veins
   Invest Ophthalmol Vis. Sci. 1993, 34(Suppl): 927
2. H.Tagawa, H. Furukawa and H. Fujii
   Dynamic Ocular Blood Flow Image Using Laser Speckle Flowgraphy
   Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995.
3. Hiroshi Tagawa, Hideki Furukawa and Hitoshi Fujii
   Changes of Blood Circulation in Human Eyes with Retinal Diseases Using Real-Time Laser Flowgraphy
   Proc. 3rd Internet World Congress on Biomedical Sciences, 1996
4. Tagawa H, Kawaguchi S,Furukawa H, and Fujii H.
   Effect of retrobulbar injection of unoprostone on the rabbit ocular microcirculation
   Invest Ophthalmol Vis Sci 1997, 38(Suppl): 782
5. Kawaguchi S, Tagawa H, Maeda T, Suzuki J, and Fujii H.
   Circulatory changes of retinal vessels and choroidal microcirculation in eyes with arterial occlusive disease
   Invest Ophthalmol Vis Sci 1997, 38(Suppl): 1047
6. Tagawa H, Nakagawa H,Furukawa H, and Fujii H.
   Visualization and quantitative evaluation of pulsatile ocular microcirculation by laser speckle flowgraphy
   Invest Ophthalmol Vis Sci 1998, 39(Suppl): 267
7. Sasaki N, Tagawa H, Katsuta S, Nakagawa T andFujii H.
   Long term effects of oral prostaglandin on retinal artery, optic nerve head, and choroidal micricirculation in normals
   Invest Ophthalmol Vis Sci 1998, 39(Suppl): 271
8. Tashimo A,Tagawa H, Kawaguchi S, Suzuki T, Nakagawa T and Fujii H.
   Effects of oral prostaglandin on retinal artery, optic nerve head, and choroidal micricirculation in eyes with arterial occlusive disease
   Invest Ophthalmol Vis Sci 1998, 39(Suppl): 999
9. Katsuta S, Tagawa H, Suzuki T, Sasaki N, Nakagawa T and Fujii H.
   Short term effects of oral prostaglandin on retinal artery, optic nerve head, and choroidal micricirculation in normals
   Invest Ophthalmol Vis Sci 1998, 39(Suppl): 1000
10. Tagawa H,Sasaki N,Tashimo A, Suzuki T, Shimizu M, Fujii H.
    Estimation of real blood velocity measured by laser speckle flowgraphy at retinal vessels
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 369
11. Sasaki N, Tagawa H, Shimizu M, Suzuki T, Fujii H.
    Changes of pulsatility at retinal arteries as aging
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 488
12. Katsuta S,Shimizu M, Tagawa H, Sasaki N, Suzuki T, Fujii H.
    Changes of pulsatility at choroidal microcirculation as aging
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 488
13. Tashimo A, Tagawa H, Sasaki N, Suzuki T, Fujii H.
    Changes of pulsatility at retinal arteries and choroidal microcirculation in patients with arteriosclerosis
    Invest Ophthalmol Vis Sci 1999, 40(Suppl): 681
14. Kimihito Maeda, Futoshi Ishikawa, Hiroshi Ohguro
    Ocular blood flow levels and visual prognosis in a patient with nonischemic type central retinal vein occlusion
    Clinical Ophthalmology 2009:3 489-491
15. Hiroshi Ohguro, Ikuyo Ohguro, Maki Katai, Sachie Tanaka
    Two-Year Randomized, Placebo-Controlled Study of Black Currant Anthocyanins on Visual Field in Glaucoma
    Ophthalmologica(DOI: 10.1159/000335961), 2012.
16. Ikuyo Ohguro, Hiroshi Ohguro
    The Effects of a Fixed Combination of 0.5% Timolol and 1% Dorzolamide on Optic Nerve Head Blood Circulation
    Journal of Ocular Pharmacology and Therapeutics (doi:10.1089/jop.2011.0243.), 2012.
17. Fumihito Hikage, Masato Furuhashi, Yosuke Ida, Hiroshi Ohguro, Megumi Watanabe, Soma Suzuki and Kaku Itoh
    Fatty acid-binding protein 4 is an independent factor in the pathogenesis of retinal vein occlusion
    PLOS ONE, 16(1), e0245763, doi:10.1371/journal.pone.0245763, 2021.
18. Kaku Itoh, Masato Furuhashi, Yosuke Ida, Hiroshi Ohguro, Megumi Watanabe, Soma Suzuki and Fumihito Hikage
    Detection of significantly high vitreous concentrations of fatty acid-binding protein 4 in patients with proliferative diabetic retinopathy
    Scientific Reports, 11(1), 1-10, doi:10.1038/s41598-021-91857-1, 2021.

Department of Cardiac Surgery, Asahikawa Medical University

1. Fumiaki Kimura, Hirotsugu Kanda, Yuki Toyama, Takayuki Kunisawa, Taiji Nagaoka, Akitoshi Yoshida, Hiroto Kitahara and Hiroyuki Kamiya
   Evaluation of cerebral circulation during retrograde perfusion by laser speckle flowgraphy
   General Thoracic and Cardiovascular Surgery, doi:10.1007/s11748-016-0727-z, 2016.
2. Hiroto Kitahara, Hirotsugu Kanda, Fumiaki Kimura, Tomohiro Takeda, Shingo Kunioka, Takayuki Kunisawa and Hiroyuki Kamiya
   Cerebral circulation estimated by laser speckle flowgraphy in retrograde femoral arterial perfusion during minimally invasive cardiac surgery.
   Interactive cardiovascular and thoracic surgery, 25(1), 25-29, doi:10.1093/icvts/ivx046, 2017.

Department of Anesthesiology and Crcal care, Asahikawa Medical University

1. Hirotsugu Kanda, Fumiaki Kimura, Takafumi Iida, Megumi Kanao-Kanda, Takayuki Kunisawa, Taiji Nagaoka, Akitoshi Yoshida and Hiroyuki Kamiya
   Combined Use of Intra-aortic Balloon Pump and Venoarterial Extracorporeal Membrane Oxygenation Support With Femoral Arterial Cannulation Impairs Cerebral Microcirculation: Evaluation With Laser Speckle Flowgraphy
   Journal of Cardiothoracic and Vascular Anesthesia, doi:10.1053/j.jvca.2016.09.012, 2016.
2. Hirotsugu Kanda, Hiroto Kitahara, Yuki Toyama, Megumi Kanao-Kanda, Takayuki Kunisawa and Hiroyuki Kamiya
   Intra-aortic Balloon Pump Does Not Impede Cerebral Microcirculation During Central Extracorporeal Membrane Oxygenation Support: Evaluation With Laser Speckle Flowgraphy
   Journal of Cardiothoracic and Vascular Anesthesia, 31(4), e67-e68, doi:10.1053/j.jvca.2017.04.030, 2017.
3. Hirotsugu Kanda, TakayukiKunisawa, Hiroto Kitahara, Takafumi Iida, Yuki Toyama, Megumi Kanao-Kanda, Chie Mori and Hiroyuki Kamiya
   Cerebral Hypoxia Caused by Flow Confliction During Minimally Invasive Cardiac Surgery With Retrograde Perfusion: A Word of Caution
   Journal of Cardiothoracic and Vascular Anesthesia, 32(4), 1838-1840, doi:10.1053/j.jvca.2017.10.007, 2017.
4. Hirotsugu Kanda, Takayuki Kunisawa, Takafumi Iida, Masahiro Tada, Fumiaki Kimura, Hayato Ise and Hiroyuki Kamiya
   Cerebral circulation during retrograde cerebral perfusion: evaluation using laser speckle flowgraphy
   The Annals of Thoracic Surgery, doi:10.1016/j.athoracsur.2018.11.067, 2018.
5. Megumi Kanao-Kanda, Hirotsugu Kanda, Takafumi Iida, Shinsuke Kikuchi and Nobuyoshi Azuma
   Clinical Application of Laser Speckle Flowgraphy to Assess Changes in Blood Flow to the Foot After a Lumbar Sympathetic Ganglion Block: A Case Report
   Journal of Pain Research, 14, 1451-1456, doi:10.2147/JPR.S305543, 2021.

Department of Ophthalmology, Tohoku University

1. Naoko Aizawa, Yu Yokoyama, Naoki Chiba, Kazuko Omodaka, Masayuki Yasuda, Takaaki Otomo, Masahiko Nakamura, Nobuo Fuse, Toru Nakazawa
   Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma
   Clinical Ophthalmology, 2011:5, 1171-1176
2. Naoki Chiba, Kazuko Omodaka, Yu Yokoyama, Naoko Aizawa, Satoru Tsuda, Masayuki Yasuda, Takaaki Otomo, Shunji Yokokura, Nobuo Fuse, Toru Nakazawa
   Association between optic nerve blood flow and objective examinations in glaucoma patients with generalized enlargement disc type
   Clinical Ophthalmology, 2011:5, 1549-1556
3. Yu Yokoyama, Naoko Aizawa, Naoki Chiba, Kazuko Omodaka, Masahiko Nakamura, Takaaki Otomo, Shunji Yokokura, Nobuo Fuse, Toru Nakazawa
   Significant correlations between optic nerve head microcirculation and visual field defects and nerve fiber layer loss in glaucoma patients with myopic glaucomatous disk
   Clinical Ophthalmology, 2011:5, 1721 - 1727
4. Tsuda, Satoru MD; Yokoyama, Yu MD; Chiba, Naoki MD; Aizawa, Naoko MD; Shiga, Yukihiro MD; Yasuda, Masayuki MD; Yokokura, Shunji PhD, MD; Otomo, Takaaki MD; Fuse, Nobuo PhD, MD; Nakazawa, Toru PhD, MD
   Effect of Topical Tafluprost on Optic Nerve Head Blood Flow in Patients With Myopic Disc Type
   Journal of Glaucoma, POST AUTHOR CORRECTIONS, 2 April 2013, doi: 10.1097/IJG.0b013e318237c8b3
5. Naoko Aizawa MD, Hiroshi Kunikata MD PhD, Yu Yokoyama MD, Toru Nakazawa MD PhD
   Correlation between optic disc microcirculation in glaucoma measured with laser speckle flowgraphy and fluorescein angiography, and the correlation with mean deviation
   Clinical & Experimental Ophthalmology, DOI: 10.1111/ceo.12130
6. Yukihiro Shiga, Masahiko Shimura, Toshifumi Asano, Satoru Tsuda, Yu Yokoyama, Naoko Aizawa,
   Kazuko Omodaka, Morin Ryu, Shunji Yokokura, Takayuki Takeshita and Toru Nakazawa
   The Influence of Posture Change on Ocular Blood Flow in Normal Subjects, Measured by Laser Speckle Flowgraphy
   Current Eye Research, June 2013, Vol. 38, No. 6 , Pages 691-698 (doi:10.3109/02713683.2012.758292)
7. Yukihiro Shiga, Kazuko Omodaka, Hiroshi Kunikata, Morin Ryu, Yu Yokoyama, Satoru Tsuda, Toshifumi Asano, Shigeto Maekawa, Kazuichi Maruyama, Toru Nakazawa
   Waveform analysis of ocular blood flow and the early detection of normal-tension glaucoma
   IOVS, October 15, 2013 IOVS-13-12930(doi:10.1167/iovs.13-12930)
8. Shin Takayama, Yukihiro Shiga, Taiki Kokubun, Hideyuki Konno, Noriko Himori, Morin Ryu, Takehiro Numata, Soichiro Kaneko, Hitoshi Kuroda, Junichi Tanaka, Seiki Kanemura, Tadashi Ishii, Nobuo Yaegashi, Toru Nakazawa
   The tradonal kampo medicine tokishakuyakusan increases ocular blood flow in healthy subjects
   Evidence-Based Complementary and Alternative Medicine, 2014.
9. Satoru Tsuda, Hiroshi Kunikata, Masahiko Shimura, Naoko Aizawa, Kazuko Omodaka, Yukihiro Shiga, Masayuki Yasuda, Yu Yokoyama, Toru Nakazawa
   Pulse-Waveform Analysis of Normal Population using Laser Speckle Flowgraphy
   Current Eye Research, Posted online on April 21, 2014. (doi:10.3109/02713683.2014.905608)
10. Yukihiro Shiga, Toshifumi Asano, Hiroshi Kunikata, Fumihiko Nitta, Hajime Sato, Toru Nakazawa and Masahiko Shimura
    Relative flow volume, a novel blood flow index in the human retina derived from laser speckle flowgraphy
    Investigative Ophthalmology & Visual Science, IOVS-14, 2014. (doi: 10.1167/iovs.14-14116)
11. Fumihiko Nitta, Hiroshi Kunikata, Naoko Aizawa, Kazuko Omodaka, Yukihiro Shiga, Masayuki Yasuda and Toru Nakazawa
    The effect of intravitreal bevacizumab on ocular blood flow in diabetic retinopathy and branch retinal vein occlusion as measured by laser speckle flowgraphy
    Clinical Ophthalmology, 2014:8, 1119 - 1127
12. Naoko Aizawa, Hiroshi Kunikata, Yu Yokoyama and Toru Nakazawa
    Correlation between optic disc microcirculation in glaucoma measured with laser speckle flowgraphy and fluorescein angiography, and the correlation with mean deviation
    Clinical & experimental ophthalmology, 42(3), 293-294.
13. Shunsuke Omodaka, Hidenori Endo, Hiroshi Doi, Hiroaki Shimizu, Miki Fujimura, Naoko Aizawa, Toru Nakazawa and Teiji Tominaga
    Usefulness of Laser Speckle Flowgraphy for the Assessment of Ocular Blood Flow in Extracranial Intracranial Bypass
    Journal of Stroke and Cerebrovascular Diseases (2014).
14. Naoko Aizawa, Hiroshi Kunikata, Yukihiro Shiga, Yu Yokoyama, Kazuko Omodaka and Toru Nakazawa
    Correlation between structure/function and optic disc microcirculation in myopic glaucoma, measured with laser speckle flowgraphy.
    BMC Ophthalmology, 14(1), 113.
15. Naoko Aizawa, Fumihiko Nitta, Hiroshi Kunikata, Tetsuya Sugiyama, Tsunehiko Ikeda, Makoto Araie and Toru Nakazawa
    Laser speckle and hydrogen gas clearance measurements of optic nerve circulation in albino and pigmented rabbits with or without optic disc atrophy.
    Investigative Ophthalmology & Visual Science, IOVS-14, 2014. doi: 10.1167/iovs.14-15373
16. Wataru Kobayashi, Hiroshi Kunikata, Kazuko Omodaka, Kyousuke Togashi, Morin Ryu, Masahiro Akiba, Gaku Takeuchi, Tetsuya Yuasa, and Toru Nakazawa
    Correlation of Optic Nerve Microcirculation with Papillomacular Bundle Structure in Treatment Naive Normal Tension Glaucoma
    Journal of Ophthalmology, vol. 2014, Article ID 468908, 9 pages, 2014. doi:10.1155/2014/468908
17. Hiroshi Kunikata, Naoko Aizawa, Masataka Kudo, Shunji Mugikura, Fumihiko Nitta, Ryo Morimoto, Yoshitsugu Iwakura, Yoshikiyo Ono, Fumitoshi Satoh, Hidetoshi Takahashi, Sadayoshi Ito, Shoki Takahashi and Toru Nakazawa
    Relationship of Ocular Microcirculation, Measured by Laser Speckle Flowgraphy, and Silent Brain Infarction in Primary Aldosteronism
    PLOS ONE, 10(2), e0117452, 2015.
18. Noriko Himori, Hiroshi Kunikata, Yukihiro Shiga, Kazuko Omodaka, Kazuichi Maruyama, Hidetoshi Takahashi and Toru Nakazawa
    The association between systemic oxidative stress and ocular blood flow in patients with normal-tension glaucoma
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1-9, 2015.
19. Hiroshi Kunikata, Toru Nakazawa
    Recent Clinical Applications of Laser Speckle Flowgraphy in Eyes with Retinal Disease.
    The Asia-Pacific Journal of Ophthalmology, 2015
20. Naoko Aizawa, Hiroshi Kunikata, Fumihiko Nitta, Yukihiro Shiga, Kazuko Omodaka, Satoru Tsuda and Toru Nakazawa
    Age-and Sex-Dependency of Laser Speckle Flowgraphy Measurements of Optic Nerve Vessel Microcirculation.
    PLOS ONE, 11(2), e0148812, 2016.
21. Toru Nakazawa
    Ocular Blood Flow and Influencing Factors for Glaucoma.
    The Asia-Pacific Journal of Ophthalmology, 5(1), 38-44, 2016.
22. Maki Inoue, Noriko Himori, Hiroshi Kunikata, Takayuki Takeshita, Naoko Aizawa, Yukihiro Shiga,Kazuko Omodaka, Koji M Nishiguchi, Hidetoshi Takahashi and Toru Nakazawa
    The reduction of temporal optic nerve head microcirculation in autosomal dominant optic atrophy
    Acta ophthalmologica, 94(7), e580-e585, doi:10.1111/aos.12999, 2016.
23. Kazuko Omodaka, Seri Takahashi, Akiko Matsumoto, Shigeto Maekawa, Tsutomu Kikawa, Noriko Himori, Hidetoshi Takahashi, Kazuichi Maruyama, Hiroshi Kunikata, Masahiro Akiba and Toru Nakazawa
    Clinical Factors Associated with Lamina Cribrosa Thickness in Patients with Glaucoma, as Measured with Swept Source Optical Coherence Tomography
    PLOS ONE, 11(4), e0153707, 2016.
24. Kazuki Hashimoto, Hiroshi Kunikata, Masayuki Yasuda, Azusa Ito, Naoko Aizawa, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Yoshimasa Takano, Koji M. Nishiguchi, Hideki Katagiri and Toru Nakazawa
    The relationship between advanced glycation end products and ocular circulation in type 2 diabetes
    Journal of Diabetes and its Complications, 2016.
25. Yukihiro Shiga, Hiroshi Kunikata, Naoko Aizawa, Naoki Kiyota, Yukiko Maiya, Yu Yokoyama, Kazuko Omodaka, Hidetoshi Takahashi, Tomoki Yasui, Keiichi Kato, Aiko Iwase and Toru Nakazawa
    Optic Nerve Head Blood Flow, as Measured by Laser Speckle Flowgraphy, Is Significantly Reduced in Preperimetric Glaucoma
    Current Eye Research, doi:10.3109/02713683.2015.1127974, 2016.
26. Naoki Kiyota, Hiroshi Kunikata, Yukihiro Shiga, Kazuko Omodaka and Toru Nakazawa
    Relationship between laser speckle flowgraphy and optical coherence tomography angiography measurements of ocular microcirculation
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-017-3627-8, 1-10, 2017.
27. Naoki Kiyota, Yukihiro Shiga, Shiori Suzuki, Marika Sato, Naoko Takada, Shigeto Maekawa, Kazuko Omodaka, Kazuichi Maruyama, Hiroshi Kunikata and Toru Nakazawa
    The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients
    Investigative Ophthalmology and Visual Science, 58(7), 3181-3188, doi: 10.1167/iovs.17-21648, 2017.
28. Kazuichi Maruyama, Aya Noguchi, Ai Shimizu, Yukihiro Shiga, Hiroshi Kunikata and Toru Nakazawa
    Predictors of Recurrence in Vogt-Koyanagi-Harada Disease
    Ophthalmology Retina, doi: 10.1016/j.oret.2017.07.016, 2017.
29. Naoki Kiyota, Hiroshi Kunikata, Seri Takahashi, Yukihiro Shiga, Kazuko Omodaka and Toru Nakazawa
    Factors associated with deep circulation in the peripapillary chorioretinal atrophy zone in normal-tension glaucoma with myopic disc
    Acta Ophthalmologica, doi:10.1111/aos.13621, 2017.
30. Naoko Aizawa, Hiroshi Kunikata, Yukihiro Shiga, Satoru Tsuda, Yu Yokoyama, Kazuko Omodaka, Tomoki Yasui, Keiichi Kato, Hiroaki Kurashima, Etsuyo Miyamoto, Masayo Hashimoto and Toru Nakazawa
    Preperimetric Glaucoma Prospective Observational Study (PPGPS): Design, baseline characteristics, and therapeutic effect of tafluprost in preperimetric glaucoma eye
    PLOS ONE, 12(12), e0188692, doi:10.1371/journal.pone.0188692, 2017.
31. Yukihiro Shiga, Koji M. Nishiguchi, Yosuke Kawai, Kaname Kojima, Kota Sato, Kosuke Fujita, Mai Takahashi, Kazuko Omodaka, Makoto Araie, Kenji Kashiwagi, Makoto Aihara, Takeshi Iwata, Fumihiko Mabuchi, Mitsuko Takamoto, Mineo Ozaki, Kazuhide Kawase, Nobuo Fuse, Masayuki Yamamoto, Jun Yasuda, Masao Nagasaki, Toru Nakazawa , for the Japan Glaucoma Society Omics Group (JGS-OG)
    Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7.
    PloS one, 12(12), e0186678, doi:10.1371/journal.pone.0186678, 2017.
32. Kazuko Omodaka, Guangzhou An, Satoru Tsuda, Yukihiro Shiga, Naoko Takada, Tsutomu Kikawa, Hidetoshi Takahashi, Hideo Yokota, Masahiro Akiba and Toru Nakazawa
    Classification of optic disc shape in glaucoma using machine learning based on quantified ocular parameters
    PloS one, 12(12), e0190012, doi:10.1371/journal.pone.0190012, 2017.
33. Yukihiro Shiga, Naoko Aizawa, Satoru Tsuda, Yu Yokoyama, Kazuko Omodaka, Hiroshi Kunikata, Tomoki Yasui, Keiichi Kato, Hiroaki Kurashima, Etsuyo Miyamoto, Masayo Hashimoto and Toru Nakazawa
    Preperimetric Glaucoma Prospective Study (PPGPS): Predicting Visual Field Progression With Basal Optic Nerve Head Blood Flow in Normotensive PPG Eyes
    Translational vision science and technology, 7(1), 11, doi:10.1167/tvst.7.1.11, 2018.
34. Naoki Kiyota, Hiroshi Kunikata, Yukihiro Shiga, Kazuko Omodaka and Toru Nakazawa
    Ocular microcirculation measurement with laser speckle flowgraphy and optical coherence tomography angiography in glaucoma.
    Acta Ophthalmologica, doi:10.1111/aos.13639, 2018.
35. Naoki Kiyota, Yukihiro Shiga, Kohei Ichinohasama, Masayuki Yasuda, Naoko Aizawa, Kazuko Omodaka, Naoto Honda, Hiroshi Kunikata and Toru Nakazawa
    The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow
    Investigative Ophthalmology & Visual Science, 59(8), 3488-3496, 2018.
36. Maki Inoue-Yanagimachi, Noriko Himori, Kota Sato, Taiki Kokubun, Toshifumi Asano, Yukihiro Shiga, Satoru Tsuda, Hiroshi Kunikata and Toru Nakazawa
    Association between mitochondrial DNA damage and ocular blood flow in patients with glaucoma
    Brsh Journal of Ophthalmology, doi:10.1136/bjophthalmol-2018-312356, 2018.
37. Kohei Ichinohasama, Hiroshi Kunikata, Azusa Ito, Masayuki Yasuda, Shojiro Sawada, Keiichi Kondo, Chihiro Satake, Hideki Katagiri and Toru Nakazawa
    The Relationship between Carotid Intima-Media Thickness and Ocular Circulation in Type-2 Diabetes
    Journal of Ophthalmology, doi:10.1155/2019/3421305, 2019.
38. Naoki Kiyota, Yukihiro Shiga, Masayuki Yasuda, Naoko Aizawa, Kazuko Omodaka, Satoru Tsuda, Hiroshi Kunikata and Toru Nakazawa
    Sectoral Differences in the Association of Optic Nerve Head Blood Flow and Glaucomatous Visual Field Defect Severity and Progression
    Investigative Ophthalmology & Visual Science, 60(7), 2650-2658, doi:10.1167/iovs.19-27230, 2019.
39. Toru Nakazawa, Takeo Fukuchi
    What is glaucomatous optic neuropathy?
    Japanese Journal of Ophthalmology, 64(3), 243–249, doi:10.1007/s10384-020-00736-1, 2020.
40. Toshifumi Asano, Hiroshi Kunikata, Masayuki Yasuda, Koji M. Nishiguchi, Toshiaki Abe and Toru Nakazawa
    Ocular microcirculation changes, measured with laser speckle flowgraphy and optical coherence tomography angiography, in branch retinal vein occlusion with macular edema treated by ranibizumab
    International Ophthalmology, doi:10.1007/s10792-020-01562-7, 2020.
41. Naoki Kiyota, Yukihiro Shiga, Kazuko Omodaka, Kyongsun Pak and Toru Nakazawa
    Time-course Changes in Optic Nerve Head Blood Flow and Retinal Nerve Fiber Layer Thickness in Eyes with Open-angle Glaucoma
    Ophthalmology, doi:10.1016/j.ophtha.2020.10.010, 2020.
42. Masayuki Yasuda, Hajime Sato, Kazuki Hashimoto, Urara Osada, Takehiro Hariya, Hiroko Nakayama, Toshifumi Asano, Noriyuki Suzuki, Tatsu Okabe, Mai Yamazaki, Megumi Uematsu, Masanori Munakata and Toru Nakazawa
    Carotid artery intima-media thickness, HDL cholesterol levels, and gender associated with poor visual acuity in patients with branch retinal artery occlusion
    PloS one, 15(10), e0240977, doi:10.1371/journal.pone.0240977, 2020.
43. Nana Takahashi, Hiroshi Kunikata, Masayuki Yasuda, Takehiro Hariya, Koji M. Nishiguchi and Toru Nakazawa
    Polypoidal choroidal vasculopathy in a case of retins pigmentosa, successfully treated with intravitreal aflibercept
    American Journal of Ophthalmology Case Reports, 101123, doi:10.1016/j.ajoc.2021.101123, 2021.

Department of Obstetrics and Gynecology, Tohoku University

1. Takahiro Sato, Junichi Sugawara , Naoko Aizawa, Noriyuki Iwama, Fumiaki Takahashi, Michiyo Nakamura-Kurakata, Masatoshi Saito, Takashi Sugiyama, Hiroshi Kunikata, Toru Nakazawa and Nobuo Yaegashi
   Longitudinal changes of ocular blood flow using laser speckle flowgraphy during normal pregnancy
   PLOS ONE, 12(3), e0173127, doi:10.1371/journal.pone.0173127, 2017.

Department of Ophthalmology, Akita University

1. Yusuke Ohta, Sanae Takaseki and Takeshi Yoshitomi
   Effects of ripasudil hydrochloride hydrate (K-115), a Rho-kinase inhibitor, on ocular blood flow and ciliary artery smooth muscle contraction in rabbits
   Japanese journal of ophthalmology, 61(5), 423–432, 2017.
2. Ya-Ru Dong, Shi-Wei Huang, Ji-Zhe Cui and Takeshi Yoshitomi
   Effects of brinzolamide on rabbit ocular blood flow in vivo and ex vivo
   International Journal of Ophthalmology, 11(5), 719–725, 2018.

Department of Ophthalmology, Gunma University

1. Hiroaki Isono, Shoji Kishi, Yasutaka Kimura, Naoya Hagiwara, Naoki Konishi and Hitoshi Fujii
   Observation of Choroidal Circulation Using Index of Erythrocytic Velocity
   Arch Ophthalmol, 121, no.2, 225-231, 2003.
2. A. Otsubo, S. Kishi, K. Ohkoshi and T. Ymaguchi
   The Influence of Peripheral Retinal Detachment in Choroidal Blood Flow of the Macula
   ARVO, 2003, (3004/B843)
3. Watanabe G, Fujii H, Kishi S
   Imaging of Choroidal Hemodynamics in Eyes with Polypoidal Choroidal Vasculopathy Using Laser Speckle Phenomenon
   Jpn J Ophthalmol 52: 204-210, 2008
4. Yoichiro Shinohara, Tomoyuki Kashima, Hideo Akiyama, Shoji Kishi
   Alteration of choroidal thickness in a case of carotid cavernous fistula: a case report and a review of the literature
   BMC Ophthalmology 2013, 13:75 doi:10.1186/1471-2415-13-75
5. Yoichiro Shinohara, Tomoyuki Kashima, Hideo Akiyama, Yukitoshi Shimoda, Danjie Li and Shoji Kishi
   Evaluation of Fundus Blood Flow in Normal Individuals and Patients with Internal Carotid Artery Obstruction Using Laser Speckle Flowgraphy
   PLOS ONE, 12(1), e0169596, 2017.

Department of Neurosurgery, Saitama Medical Center, Saitama Medical University

1. Shinsuke Yoshida, Soichi Oya, Hiroto Obata, Naoaki Fujisawa, Tsukasa Tsuchiya, Takumi Nakamura, Masahiro Indo, Masaaki Shojima and Toru Matsui
   Carotid endarterectomy restores decreased vision due to chronic ocular ischemia
   Acta Neurochir, doi:10.1007/s00701-020-04603-3, 2020.

Department of Ophthalmology, Niigata University

1. Kiyoshi Yaoeda, Motohiro Shirakashi, Shigeo Funaki, Haruko Funaki, Tomoko Nakatsue, Atsushi Fukushima
   Measurement of Microcirculation in the Optic Nerve Head by Laser Speckle Flowgraphy and Scanning Laser Doppler Flowmetry.
   Am. J. Ophthalmol., 129, NO. 6, 734-739, 2000.
2. Kiyoshi Yaoeda, Motohiro Shirakashi, Shigeo Funaki, Haruko Funaki, Tomoko Nakatsue, Atsushi Fukushima AND Haruki Abe
   Measurement of Microcirculation in Optic Nerve Head by Laser Speckle Flowgraphy in Normal Volunteers
   Am. J. Ophthalmol., 130, NO. 5, 606-610, 2000.
3. Kiyoshi Yaoeda, Motohiro Shirakashi, Atsushi Fukushima, Shigeo Funaki, Haruko Funaki, Haruki Abe and Naohito Tanabe
   Relationship between optic nerve head microcirculation and visual field loss in glaucoma.
   Acta Ophthalmol. Scand, 81, 253-259, 2003.

Department of Ophthalmology, University of Toyama

1. Yuta Takata, Yasuhito Nitta, Akio Miyakoshi and Atsushi Hayashi
   Retinal Endovascular Surgery with Tissue Plasminogen Activator Injection for Central Retinal Artery Occlusion
   Case Reports in Ophthalmology, 9(2), 327-332, doi:10.1159/000489696, 2018.
2. Shinya Abe, Tomoko Nakamura, Erika Okumura, Toshihiko Oiwake, Annabelle A. Okada and Atsushi Hayashi
   Long-term changes of choroidal blood flow velocity in Vogt-Koyanagi-Harada disease
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-021-05540-2, 2022.

Department of Ophthalmology, Toho University Sakura Medical Center

1. Tomoaki Shiba, Mao Takahashi, Yuichi Hori and Takatoshi Maeno
   Pulse-wave analysis of optic nerve head circulation is significantly correlated with brachialankle pulse-wave velocity, carotid intima media thickness, and age
   Graefe's Archive for Clinical and Experimental Ophthalmology (DOI: 10.1007/s00417-012-1952-5), 2012.
2. Shiba T, Takahashi M, Hori Y, Maeno T, Shirai K.
   Optic Nerve Head Circulation Determined by Pulse Wave Analysis is Significantly Correlated with Cardio Ankle Vascular Index, Left Ventricular Diastolic Function, and Age.
   Journal of atherosclerosis and thrombosis, Published online: July 4, 2012.
3. Tomoaki Shiba, Mao Takahashi, Takatoshi Maeno
   Pulse-Wave Analysis of Optic Nerve Head Circulation Is Significantly Correlated With Kidney Function in Patients With and Without Chronic Kidney Disease
   Journal of Ophthalmology, 2013.
4. Makoto Ubuka, Tetsuya Sugiyama, Yasutaka Onoda, Tomoaki Shiba, Yuichi Hori, Takatoshi Maeno
   Changes in the Blood Flow of the Optic Nerve Head Induced by Different Concentrations of Epinephrine in Intravitreal Infusion During Vitreous Surgery
   Investigative Ophthalmology & Visual Science, 2014, IOVS-13-13801.
5. Muramatsu Rina, Tomoaki Shiba, Mao Takahashi, Yuichi Hori and Takatoshi Maeno
   Pulse waveform analysis of optic nerve head circulation for predicting carotid atherosclerotic changes.
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-015-3123-y, 2015.
6. Ryuya Hashimoto, Asato Hirota and Takatoshi Maeno
   Choroidal blood flow impairment demonstrated using laser speckle flowgraphy in a case of commotio retinae
   American Journal of Ophthalmology Case Reports, doi: 10.1016/j.ajoc.2016.08.002, 2016.
7. Ryuya Hashimoto, Tetsuya Sugiyama, Makoto Ubuka and Takatoshi Maeno
   Autoregulation of Optic Nerve Head Blood Flow Induced by Elevated Intraocular Pressure during Vitreous Surgery.
   Current Eye Research, doi: 10.1080/02713683.2016.1220592, 2016.
8. Ryuya Hashimoto, Tetsuya Sugiyama, Hidetaka Masahara, Masashi Sakamoto, Makoto Ubuka and Takatoshi Maeno
   Impaired Autoregulation of Blood Flow at the Optic Nerve Head during Vitrectomy in Patients with Type 2 Diabetes
   American Journal of Ophthalmology, doi: 10.1016/j.ajo.2017.06.021, 2017.
9. Ryuya Hashimoto, Tetsuya Sugiyama, Makoto Ubuka and Takatoshi Maeno
   Impairment of autoregulation of optic nerve head blood flow during vitreous surgery in patients with hypertension and hyperlipidemia
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-017-3788-5, 2017.
10. Ryuya Hashimoto, Juri Kawamura, Asato Hirota, Mizuho Oyamada, Asao Sakai and Takatoshi Maeno
    Changes in choroidal blood flow and choroidal thickness after treatment in two cases of pediatric anisohypermetropic amblyopia
    American Journal of Ophthalmology Case Reports, Volume 8, 39-43, doi: 10.1016/j.ajoc.2017.10.010, 2017.
11. Ryuya Hashimoto, Tetsuya Sugiyama and Takatoshi Maeno
    Comparison of Optic Nerve Head Blood Flow Autoregulation among Quadrants Induced by Decreased Ocular Perfusion Pressure during Vitrectomy
    BioMed Research International, vol. 2017, Article ID 6041590, 6 pages, doi:10.1155/2017/6041590, 2017.
12. Ryuya Hashimoto, Mizuho Oyamada and Takatoshi Maeno
    Analysis of Optic Nerve Head Circulation Using Laser Speckle Flowgraphy in a Case of Pediatric Optic Neurs
    EC Ophthalmology, 9(8), 572-581, 2018.
13. Ryo Yamazaki, Ryuya Hashimoto, Hidetaka Masahara, Masashi Sakamoto and Takatoshi Maeno
    Time Course in Ocular Blood Flow and Pulse Waveform in a Case of Ocular Ischemic Syndrome with Intraocular Pressure Fluctuation
    Vision, 4(2), 31, doi:10.3390/vision4020031, 2020.
14. Keisuke Yata, Ryuya Hashimoto, Hidetaka Masahara, Mizuho Oyamada and TakatoshiMaeno
    Changes in choroidal circulation and pulse waveform in a case of pregnancy-induced hypertension with serous retinal detachment
    American Journal of Ophthalmology Case Reports, 100911, doi:10.1016/j.ajoc.2020.100911, 2020.

Department of Ophthalmology, Toho University Omori Medical Center

1. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Yuuji Katayama, Tetsushi Arimura, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
   Reproducibility of Neonate Ocular Circulation Measurements using Laser Speckle Flowgraphy
   BioMed Research International, 2015.
2. Tomoaki Shiba, Tetsuya Sugiyama, Yuichi Hori, Tadashi Matsumoto, Takatoshi Maeno and Mao Takahashi
   Relationship between plasma levels of vasoactive mediators and optic nerve head circulation shown by laser speckle flowgraphy
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-015-3145-5, 2015.
3. Tomoaki Shiba , Mao Takahashi, Ryuya Hashimoto, Tadashi Matsumoto and Yuichi Hori
   Pulse waveform analysis in the optic nerve head circulation reflects systemic vascular resistance obtained via a Swan–Ganz catheter.
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3289-y, 2016.
4. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Yuuji Katayama, Tetsushi Arimura, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
   Ocular blood flow values measured by laser speckle flowgraphy correlate with the postmenstrual age of normal neonates
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3362-6, 2016.
5. Chieko Shiba, Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
   Relationship between glycosylated hemoglobin A1c and ocular circulation by laser speckle flowgraphy in patients with/without diabetes mellitus
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3437-4, 2016.
6. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto, Kohji Shirai and Yuichi Hori
   Arterial stiffness shown by the cardio-ankle vascular index is an important contributor to optic nerve head microcirculation
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-016-3521-9, 2016.
7. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto, Yuichi Hori and Kohji Shirai
   Arterial Stiffness, Monitored with Cardio Ankle Vascular Index is Adjusting The Ocular Microcirculation Obtained from Laser Speckle Flowgraphy.
   Journal of Hypertension, doi: 10.1097/01.hjh.0000501307.42081.00, 2016.
8. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Kotaro Hine and Yuichi Hori
   A Change in Ocular Circulation after Photocoagulation for Retinopathy of Prematurity in a Neonate
   Case Reports in Ophthalmology, 8(1), 91-98, doi: 10.1159/000456708, 2017.
9. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
   Differences in optic nerve head microcirculation between evening and morning in patients with coronary artery disease
   Microcirculation, doi: 10.1111/micc.12386, 2017.
10. Tadashi Matsumoto, Yuta Saito, Takashi Itokawa, Tomoaki Shiba, Mari S. Oba, Haruo Takahashi and Yuichi Hori
    Retinal VEGF levels correlate with ocular circulation measured by a laser speckle-micro system in an oxygen-induced retinopathy rat model
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-017-3756-0, 2017.
11. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Relationship between Metabolic Syndrome and Ocular Microcirculation Shown by Laser Speckle Flowgraphy in a Hospital Setting Devoted to Sleep Apnea Syndrome Diagnostics
    Journal of Diabetes Research, doi: 10.1155/2017/3141678, 2017.
12. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Masahiko Tomita, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
    Decreased ocular blood flow after photocoagulation therapy in neonatal retinopathy of prematurity
    Japanese journal of ophthalmology, doi: 10.1007/s10384-017-0536-7, 2017.
13. Hironori Osamura, Tomoaki Shiba, Takashi Itokawa, Tadashi Matsumoto and Yuichi Hori
    Relationships among Ocular Blood Flow Shown by Laser Speckle Flowgraphy, Retinal Arteriosclerotic Change, and Chorioretinal Circulation Time Obtained by Fluorescein Angiography
    Journal of Ophthalmology, doi: 10.1155/2017/2969064, 2017.
14. Tomoaki Shiba, Mao Takahashi, Chieko Shiba, Tadashi Matsumoto and Yuichi Hori
    The relationships between the pulsatile flow form of ocular microcirculation by laser speckle flowgraphy and the left ventricular end-diastolic pressure and mass
    The International Journal of Cardiovascular Imaging, doi: 10.1007/s10554-018-1388-z, 2018.
15. Tadashi Matsumoto, Takashi Itokawa, Tomoaki Shiba, Masahiko Tomita, Kotaro Hine, Norio Mizukaki, Hitoshi Yoda and Yuichi Hori
    Intravitreal bevacizumab treatment reduces ocular blood flow in retinopathy of prematurity: a four-case report
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-018-4063-0, 2018.
16. Tetsushi Arimura, Tomoaki Shiba, Mao Takahashi, Shun Kumashiro, Hironori Osamura. Tadashi Matsumoto, Ken Sakai and Yuichi Hori
    Assessment of ocular microcirculation in patients with end-stage kidney disease
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-018-4137-z, 2018.
17. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Pulse Waveform Analysis in Ocular Microcirculation by Laser Speckle Flowgraphy in Patients with Left Ventricular Systolic and Diastolic Dysfunction
    Journal of vascular research, 55(6), 329-337, doi:10.1159/000494066, 2018.
18. Tatsuhiko Kobayashi, Tomoaki Shiba, Ayako Kinoshita, Tadashi Matsumoto and Yuichi Hori
    The influences of gender and aging on optic nerve head microcirculation in healthy adults
    Scientific Reports, 9(1), 15636, doi:10.1038/s41598-019-52145-1, 2019.
19. Tatsuhiko Kobayashi, Tomoaki Shiba, Yuji Nishiwaki, Ayako Kinoshita, Tadashi Matsumoto and Yuichi Hori
    Influence of age and gender on the pulse waveform in optic nerve head circulation in healthy men and women
    Scientific Reports, 9(1), 17895, doi:10.1038/s41598-019-54470-x, 2019.
20. Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto and Yuichi Hori
    Gender differences in the influence of obstructive sleep apnea on optic nerve head circulation
    Scientific Reports, 9(1), 18849, doi:10.1038/s41598-019-55470-7, 2019.
21. Takashi Itokawa, Takashi Suzuki, Yukinobu Okajima, Tatsuhiko Kobayashi, Hiroko Iwashita, Satoshi Gotoda, Koji Kakisu, Yuto Tei and Yuichi Hori
    Correlation between Blood Flow and Temperature of the Ocular Anterior Segment in Normal Subjects
    Diagnostics, 10(9), 695, doi:10.3390/diagnostics10090695, 2020.
22. Kento Watanabe, Tomoaki Shiba, Tetsuya Komatsu, Kiyoshi Sakuma, Megumi Aimoto, Yoshinobu Nagasawa, Akira Takahara and Yuichi Hori
    The influence of hemorrhagic shock on ocular microcirculation by obtained by laser speckle flowgraphy in a white rabbit model
    Microcirculation, e12716, doi:10.1111/micc.12716, 2021.
23. Shun Kumashiro, Seiji Takagi, Takashi Itokawa, Akiko Tajima, Tatsuhiko Kobayashi and Yuichi Hori
    Decrease in choroidal blood flow after half and one-third dose verteporfin photodynamic therapy for chronic central serous chorioretinopathy
    BMC Ophthalmology, 21(1), 1-8, doi:10.1186/s12886-021-01980-w, 2021.
24. Takashi Itokawa, Sayaka Sumazaki, Yukinobu Okajima, Koji Kakisu, Takashi Suzuki and Yuichi Hori
    Changes in ocular anterior segment blood flow and temperature after thermal pulsation treatment in patients with meibomian gland dysfunction
    Investigative Ophthalmology and Visual Science, 62(8), 1239, 2021 ARVO Annual Meeting abstract, 2021.
25. Tetsuya Komatsu, Tomoaki Shiba, Kento Watanabe, Kiyoshi Sakuma, Megumi Aimoto, Yoshinobu Nagasawa, Akira Takahara and Yuichi Hori
    Real-Time Evaluation of Regional Arterial Stiffening, Resistance, and Ocular Circulation During Systemic Administration of Adrenaline in White Rabbits
    Translational Vision Science and Technology, 10(9), 11-11, doi:10.1167/tvst.10.9.11, 2021.
26. Tatsuhiko Kobayashi, Tomoaki Shiba, Kenji Okamoto, Tomohiko Usui and Yuichi Hori
    Characteristics of laterality in the optic nerve head microcirculation obtained by laser speckle flowgraphy in healthy subjects
    Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-022-05631-8, 2022.

Department of Ophthalmology, Toho University Ohashi Medical Center

1. Ayako Anraku, Kyoko Ishida, Nobuko Enomoto, Seiji Takagi, Hiroyuki Ito, Asuka Takeyama, Fumihiko Yagi and Goji Tomita
   Association between Optic Nerve Head Microcirculation and Macular Ganglion Cell Complex Thickness in Eyes with Untreated Normal Tension Glaucoma and a Hemifield Defect
   Journal of Ophthalmology, doi: 10.1155/2017/3608396, 2017.
2. Asuka Takeyama, Kyoko Ishida, Ayako Anraku, Masahiro Ishida and Goji Tomita
   Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma
   Journal of Ophthalmology, doi: 10.1155/2018/1751857, 2018.
3. Haruka Moroi, Ayako Anraku, Kyoko Ishida and Goji Tomita
   Factors Related to a Right-Left Difference in Visual Field Defect in the Eyes with Untreated Normal Tension Glaucoma
   Journal of Ophthalmology, doi: 10.1155/2018/4595214, 2018.
4. Satoko Masai, Kyoko Ishida, Ayako Anraku, Tetsuro Takumi and Goji Tomita
   Pulse Waveform Analysis of the Ocular Blood Flow Using LaserSpeckle Flowgraphy before and after Glaucoma Treatment
   Journal of Ophthalmology, doi: 10.1155/2019/1980493, 2019.
5. Ayako Anraku, Nobuko Enomoto, Goji Tomita, Aiko Iwase, Takashi Sato, Nobuyuki Shoji, Tomoaki Shiba, Toru Nakazawa, Kazuhisa Sugiyama, Koji Nitta and Makoto Araie
   Ocular and Systemic Factors Affecting Laser Speckle Flowgraphy Measurements in the Optic Nerve Head
   Translational Vision Science & Technology, 10(1), 13, doi:10.1167/tvst.10.1.13, 2021.
6. Nobuko Enomoto, Ayako Anraku, Goji Tomita, Aiko Iwase, Takashi Sato, Nobuyuki Shoji, Tomoaki Shiba, Toru Nakazawa, Kazuhisa Sugiyama, Koji Nitta and Makoto Araie
   Characterization of laser speckle flowgraphy pulse waveform parameters for the evaluation of the optic nerve head and retinal circulation
   Scientific Reports, 11(1), 1-12, doi:10.1038/s41598-021-86280-5, 2021.

Department of Neurosurgery, Toho University Ohashi Medical Center

1. Masashi Ishii, Morito Hayashi, Fumihiko Yagi, Kenichiro Sato, Goji Tomita and Satoshi Iwabuchi
   Relationship between the Direction of Ophthalmic Artery Blood Flow and Ocular Microcirculation before and after Carotid Artery Stenting.
   Journal of Ophthalmology, doi: 10.1155/2016/2530914, 2016.

Department of Ophthalmology, University of Tokyo

1. Yasuhiro Tamaki, Eizo Kawamoto, Shuichiro Eguchi, Makoto Araie and Hitoshi Fujii
   An Application of laser speckle phenomenon for non-invasive 2-dimensional evaluation of microcirculation in ocular fundus
   Jpn. J. Ophthalmol, 37, no.2, 178-186, 1993.
2. Y. Tamaki, M. Araie, E. Kawamoto, S. Eguchi and H. Fujii
   Noncontact, Two-Dimensional Measurement of Retinal Microcirculation Using Laser Speckle Phenomenon Invest.
   Ophthalmol. Vis. Sci., 35, no.11, 3825-3834, 1994.
3. Y. Tamaki, M. Araie, E. Kawamoto, S. Eguchi and H. Fujii
   Noncontact, Two-Dimensional Measurement of Tissue Circulation in Choroid and Optic Nerve Head Using Laser Speckle Phenomenon
   Exp. Eye Res., 60, 373-384, 1995.
4. Y.Tamaki and M. Araie
   Time Change of Nicardipine Effect on Tissue Circulation in Retina in Living Rabbit eyes
   Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995
5. Y. Tamaki, M. Araie, K. Tomita, M. Nagahara, A. Tomidokoro and H. Fujii
   Real-Time Measurement of Human Optic Nerve Head and Choroid Circulation, Using the Laser Speckle Phenomenon
   Jpn. J Ophthalmol., 41, 49-54, 1997.
6. Miyuki Nagahara, Yasuhiro Tamaki, Atsuo Tomidokoro and Makoto Araie
   In Vivo Measurement of Blood Velocity in Human Major Retinal Vessels Using the Laser Speckle Method
   Invest. Ophthalmol. Vis. Sci. August 11, 2010
7. Chihiro Mayama
   Calcium channels and their blockers in intraocular pressure and glaucoma
   European Journal of Pharmacology, Available online 1 December 2013.

Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University

1. Hidetaka Noma, Kanako Yasuda, Terumi Minezaki, Sho Watarai, and Masahiko Shimura
   Changes of retinal flow volume after intravitreal injection of bevacizumab in branch retinal vein occlusion with macular edema: a case series
   BMC ophthalmology, 16(1), 61, doi:10.1186/s12886-016-0239-8, 2016.
2. Hidetaka Noma, Kanako Yasuda, Tatsuya Mimura, Akemi Ofusa, and Masahiko Shimura
   Relationship between retinal blood flow and cytokines in central retinal vein occlusion
   BMC Ophthalmology, 20(1), 215, doi:10.1186/s12886-020-01486-x, 2020.
3. Toru Mizui, Hidetaka Noma, Kanako Yasuda, Tomoe Kanemaki, Hiroshi Goto and Masahiko Shimura
   Intravitreal ranibizumab reduced ocular blood flow and aqueous cytokine levels and improved retinal morphology in patients with diabetic macular edema
   Scientific Reports, 10(1), 1-8, doi:10.1038/s41598-020-78792-3, 2020.
4. Hidetaka Noma, Kanako Yasuda, Tatsuya Mimura, Noboru Suganuma and Masahiko Shimura
   Retinal Microcirculation and Cytokines as Predictors for Recurrence of Macular Edema after Intravitreal Ranibizumab Injection in Branch Retinal Vein Occlusion
   Journal of Clinical Medicine, 10(1), 58, doi:10.3390/jcm10010058, 2020.
5. Yurika Takano, Hidetaka Noma, Kanako Yasuda, Tomoe Yamaguchi, Hiroshi Goto and Masahiko Shimura
   Retinal Blood Flow as a Predictor of Recurrence of Macular Edema after Intravitreal Ranibizumab Injection in Central Retinal Vein Occlusion
   Ophthalmic Research, doi:10.1159/000519150, 2021.

Department of Ophthalmology, Tokyo Medical and Dental University

1. Ryoko Soma, Muka Moriyama and Kyoko Ohno-Matsui
   Hemodynamics of focal choroidal excavations
   International Ophthalmology, 1-8, 2015.

Division of Ophthalmology, Nihon University

1. Taiji Nagaoka, HIrotsugu Hanazaki, Hiroyuki Nakashizuka, Hajime Onoe, Hiroshi Aso, Junya Hanaguri, Masahisa Watanabe, Harumasa Yokota and Satoru Yamagami
   Evaluation of ocular blood flow in response to induced systemic hyperoxia using a Laser Speckle Flowgraphy in anesthetized pigs
   Investigative Ophthalmology & Visual Science, 61(7), 1742, 2020.
2. Junya Hanaguri, Harumasa Yokota, Masahisa Watanabe, Lih Kuo, Satoru Yamagami and Taiji Nagaoka
   Longitudinal stability of retinal blood flow regulation in response to flicker stimulation and systemic hyperoxia in mice assessed with laser speckle flowgraphy
   Scientific Reports, 10(1), 1-9, doi:10.1038/s41598-020-75296-y, 2020.
3. Hirotsugu Hanazaki, Harumasa Yokota, Hiroshi Aso, Satoru Yamagami and Taiji Nagaoka
   Evaluation of ocular blood flow over time in a treated retinal arterial macroaneurysm using laser speckle flowgraphy
   American journal of ophthalmology case reports, 21, 101022, doi:10.1016/j.ajoc.2021.101022, 2021.
4. Harumasa Yokota, Taiji Nagaoka, Hidetaka Noma, Akemi Ofusa, Tomoe Kanemaki, Hiroshi Aso, Hirotsugu Hanazaki, Satoru Yamagami and Masahiko Shimura
   Role of ICAM-1 in impaired retinal circulation in rhegmatogenous retinal detachment
   Scientific Reports, 11(1), 1-8, doi:10.1038/s41598-021-94993-w, 2021.
5. Hanaguri J, Yokota H, Watanebe M, Yamagami S, Kushiyama A, Kuo L, Nagaoka T.
   Retinal Blood Flow Dysregulation Precedes Neural Retinal Dysfunction in Type 2 Diabetic Mice.
   Scientific Reports, 11(1), 1-11, doi:10.1038/s41598-021-97651-3, 2021.
6. Yasunari Ebuchi, daisuke fukamachi, Keisuke Kojima, Taiji Nagaoka, Nobuhiro Murata, Akihito Ohgaku, Yutaka Koyama, Hidesato Fujito, Riku Arai, Masaki Monden, Takehiro Tamaki, Daisuke Kitano, Yasuo Okumura, Satoru Yamagami
   Comprehensive Assessment of Systemic Atherosclerosis in Relation to the Ocular Resistive Index in Acute Coronary Syndrome Patients.
   Circulation, 144(Suppl_1), A8881-A8881, 2021.
7. Harumasa Yokota, Hiroki Hayashi, Junya Hanaguri, Satoru Yamagami, Akifumi Kushiyama, Hironori Nakagami and Taiji Nagaoka
   Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes
   PLOS ONE, 17(1), e0262568, doi:10.1371/journal.pone.0262568, 2022.
8. Junya Hanaguri, Harumasa Yokota, Akifumi Kushiyama, Sakura Kushiyama, Masahisa Watanabe, Satoru Yamagami and Taiji Nagaoka
   The Effect of Sodium-Dependent Glucose Cotransporter 2 Inhibitor Tofogliflozin on Neurovascular Coupling in the Retina in Type 2 Diabetic Mice
   International Journal of Molecular Sciences, 23(3), 1362, doi:10.3390/ijms23031362, 2022.
9. Junya Hanaguri, Noriaki Nagai, Harumasa Yokota, Akifumi Kushiyama, Masahisa Watanabe, Satoru Yamagami and Taiji Nagaoka
   Fenofibrate Nano-Eyedrops Ameliorate Retinal Blood Flow Dysregulation and Neurovascular Coupling in Type 2 Diabetic Mice
   Pharmaceutics, 14(2), 384, doi:10.3390/pharmaceutics14020384, 2022.

Division of Cardiology, Nihon University

1. Yasunari Ebuchi, Taiji Nagaoka, Daisuke Fukamachi, Keisuke Kojima, Naotaka Akutsu, Nobuhiro Murata, Yuki Saito, Daisuke Kitano, Harumasa Yokota, Satoru Yamagami and Yasuo Okumura
   Comprehensive assessment of systemic arteriosclerosis in relation to the ocular resistive index in acute coronary syndrome patients
   Scientific Reports, 12(1), 1-11, doi:10.1038/s41598-021-04196-6, 2022.

Department of Ophthalmology, Kyorin University

1. Toshiki Watanabe, Yukihiko Mashima, Kazuteru Kigasawa, Asako Mashima, Masahiko Shimura and Akito Hirakata
   Increased Microcirculation on Optic Nerve Head by Laser Speckle Flowgraphy at Early Stage of Leber Hereditary Optic Neuropathy
   Neuro-Ophthalmology, 43(6), 411-416, doi:10.1080/01658107.2018.1526956, 2018.

Tokyo Institute of Technology

1. Tsukasa Ikemura, Akane Miyaji, Hideaki Kashima, Yuji Yamaguchi, Naoyuki Hayashi
   Ocular blood flow decreases during passive heat stress in resting humans
   Journal of Physiological Anthropology 2013, 32:23 doi:10.1186/1880-6805-32-23
2. Tsukasa Ikemura, Naoyuki Hayashi
   Effects of Heat Stress on Ocular Blood Flow during Exhaustive Exercise
   Journal of Sports Science and Medicine (2014) 13, 172-179
3. A. Miyaji, T. Ikemura, Y. Hamada and N. Hayashi
   Regional differences in the vascular response to CO 2 among cerebral, ocular, and mesenteric vessels.
   Artery Research, Available online 6 September 2015. doi:10.1016/j.artres.2015.08.001
4. A. Miyaji, T. Ikemura and N. Hayashi
   Effect of Aging on the Blowout Time in Various Ocular Vessels
   Aging Sci, 2016, 4.148: 2.
5. Naoyuki Hayashi, Lanfei Du
   Acute and Chronic Periocular Massage for Ocular Blood Flow and Vision: a Randomized Controlled Trial
   International Journal of Therapeutic Massage & Bodywork, 14(2), 5-13, 2021.

Faculty of Sport Sciences, Waseda University

1. Tsukasa Ikemura, Hideaki Kashima, Yuji Yamaguchi, Akane Miyaji and Naoyuki Hayashi
   Inner ocular blood flow responses to an acute decrease in blood pressure in resting humans
   Physiological measurement, 36(2), 219.

Faculty of Commerce, Yokohama College of Commerce

1. Tsukasa Ikemura, Naoyuki Hayashi
   Inner ocular blood flow response to exercise in healthy humans
   The Journal of Physical Fitness and Sports Medicine, 6(4), 223-226, doi:10.7600/jpfsm.6.223, 2017.
2. Tsukasa Ikemura, Katsuhiko Suzuki, Nobuhiro Nakamura, Koichi Yada and Naoyuki Hayashi
   Fluid intake restores retinal blood flow early after exhaustive exercise in healthy subjects
   European Journal of Applied Physiology, doi:10.1007/s00421-018-3839-6, 2018.

College of Liberal Arts and Science, Kitasato University

1. Tsukasa Ikemura, Nobuhiro Nakamura, and Naoyuki Hayashi
   Impact of acute dynamic exercise on vascular stiffness in the retinal arteriole in healthy subjects
   Journal of Applied Physiology, 132(2). 459-468, doi:10.1152/japplphysiol.00507.2021, 2021.

Ophthalmology and Visual Science, Kanazawa University

1. Yasushi Wada, Tomomi Higashide, Atsushi Nagata and Kazuhisa Sugiyama
   Longitudinal Changes in Optic Nerve Head Blood Flow in Normal Rats Evaluated by Laser Speckle Flowgraphy.
   IOVS, 57(13), 5568-5575, 2016.
2. Yutaro Yamada, Tomomi Higashide, Sachiko Udagawa, Satoshi Takeshima, Kimikazu Sakaguchi, Koji Nitta and Kazuhisa Sugiyama
   The Relationship Between Interocular Asymmetry of Visual Field Defects and Optic Nerve Head Blood Flow in Patients with Glaucoma
   Journal of Glaucoma、doi:10.1097/IJG.0000000000001181, 2018.
3. Yasushi Wada, Tomomi Higashide, Atsushi Nagata and Kazuhisa Sugiyama
   Effects of ripasudil, a rho kinase inhibitor, on blood flow in the optic nerve head of normal rats
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-018-4191-6, 2018.
4. Satoshi Takeshima, Tomomi Higashide, Masayo Kimura, Sachiko Udagawa, Yutaro Yamada, Daisuke Takemoto, Shinji Ohkubo and Kazuhisa Sugiyama
   Effects of Trabeculectomy on Waveform Changes of Laser Speckle Flowgraphy in Open Angle Glaucoma
   Investigative Ophthalmology & Visual Science, 60(2), 677-684, doi:10.1167/iovs.18-25694, 2019.
5. Yasushi Wada, Tomomi Higashide, Kimikazu Sakaguchi, Atsushi Nagata, Kazuyuki Hirooka and Kazuhisa Sugiyama
   Compromised blood flow in the optic nerve head after systemic administration of 2 aldosterone in rats: A possible rat model of retinal ganglion cell loss
   Current Eye Research, doi:10.1080/02713683.2022.2029907, 2022.

Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University

1. Shinichiro Fuma, Anri Nishinaka, Yuki Inoue, Kazuhiro Tsuruma, Masamitsu Shimazawa, Mineo Kondo and Hideaki Hara
   A pharmacological approach in newly established retinal vein occlusion model
   Scientific Reports, 7, doi:10.1038/srep43509, 2017.
2. Mayu Moriguchi, Shinsuke Nakamura, Yuki Inoue, Anri Nishinaka, Maho Nakamura, Masamitsu Shimazawa and Hideaki Hara
   Irreversible Photoreceptors and RPE Cells Damage by Intravenous Sodium Iodate in Mice Is Related to Macrophage Accumulation
   Investigative Ophthalmology & Visual Science, 59(8), 3476-3487, 2018.
3. Anri Nishinaka, Yuki Inoue, Shinichiro Fuma, Yoshifumi Hida, Shinsuke Nakamura, Masamitsu Shimazawa and Hideaki Hara
   Pathophysiological Role of VEGF on Retinal Edema and Nonperfused Areas in Mouse Eyes With Retinal Vein Occlusion
   Investigative Ophthalmology & Visual Science, 59(11), 4701-4713, 2018.
4. Anri Nishinaka, Koki Nitta, Takashi Seki, Hideaki Hara and Masamitsu Shimazawa
   The Changes in Blood Flow Seen in the Eye after Foot Acupuncture Treatment in Mice
   Evidence-Based Complementary and Alternative Medicine, 2020, 6405471, doi: 10.1155/2020/6405471, 2020.

Department of Ophthalmology, Nagoya University

1. Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Kenta Murotani, Shigeyuki Matsui, and Hiroko Terasaki
   Diurnal Variations in Blood Flow at Optic Nerve Head and Choroid in Healthy Eyes: Diurnal Variations in Blood Flow.
   Medicine, 94(6): e819, 2015.
2. Kosei Yanagida, Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Hiroki Kaneko, Kenta Murotani, Shigeyuki Matsui and Hiroko Terasaki
   Sex-Related Differences in Ocular Blood Flow of Healthy Subjects Using Laser Speckle Flowgraphy.
   IOVS, 56(8), 4880-4890, 2015. doi:10.1167/iovs.15-16567
3. Takeshi Iwase, Eimei Ra, Kentaro Yamamoto, Hiroki Kaneko, Yasuki Ito and Hiroko Terasaki
   Differences of Retinal Blood Flow Between Arteries and Veins Determined by Laser Speckle Flowgraphy in Healthy Subjects
   Medicine, 94(33): e1256, 2015.
4. Takeshi Iwase, Kentaro Yamamoto, Misato Kobayashi, Eimei Ra, Kenta Murotani and Hiroko Terasaki
   What ocular and systemic variables affect choroidal circulation in healthy eyes
   Medicine, 95(43): e5102, 2016.
5. Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Kosei Yanagida, Eimei Ra and Hiroko Terasaki
   Changes in Blood Flow on Optic Nerve Head After Vitrectomy for Rhegmatogenous Retinal Detachment
   IOVS, 57(14), 6223-6233, 2016. doi:10.1167/iovs.16-20577
6. Marie Fukami, Takeshi Iwase, Kentaro Yamamoto, Hiroki Kaneko, Shunsuke Yasuda and Hiroko Terasaki
   Changes in Retinal Microcirculation After Intravitreal Ranibizumab Injection in Eyes With Macular Edema Secondary to Branch Retinal Vein Occlusion
   IOVS, 58(2), 1246-1255, 2017. doi:10.1167/iovs.16-21115
7. Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
   Effects of photocoagulation on ocular blood flow in patients with severe non-proliferative diabetic retinopathy
   PLOS ONE, 12(3), e0174427, doi:10.1371/journal.pone.0174427, 2017.
8. Marie Fukami, Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Kenta Murotani and Hiroko Terasaki
   Diurnal variation of pulse waveform parameters determined by laser speckle flowgraphy on the optic nerve head in healthy subjects.
   Medicine, 96(44): e8312, 2017.
9. Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Kosei Yanagida, Eimei Ra and Hiroko Terasaki
   Change in choroidal blood flow and choroidal morphology due to segmental scleral buckling in eyes with rhegmatogenous retinal detachment
   Scientific Reports, 7(1), 5997, doi:10.1038/s41598-017-05126-1, 2017.
10. Takeshi Iwase, Kentaro Yamamoto, Kosei Yanagida, Eimei Ra, Yasuki Ito, Kenta Murotani and Hiroko Terasaki
    Investigation of causes of sex-related differences in ocular blood flow in healthy eyes determined by laser speckle flowgraphy
    Scientific Reports, 7(1), 13878, doi:10.1038/s41598-017-14118-0, 2017.
11. Yuji Mikoshiba, Takeshi Iwase, Yoshitaka Ueno, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    A randomized clinical trial evaluating choroidal blood flow and morphology after conventional and pattern scan laser panretinal photocoagulation
    Scientific Reports, 8(1), 14128, doi:10.1038/s41598-018-32487-y, 2018.
12. Takeshi Iwase, Tomohiko Akahori, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    Evaluation of optic nerve head blood flow in response to increase of intraocular pressure
    Scientific Reports, 8(1), 17235, doi:10.1038/s41598-018-35683-y, 2018.
13. Fumi Kuroda, Takeshi Iwase, Kentaro Yamamoto, Eimei Ra and Hiroko Terasaki
    Correlation between blood flow on optic nerve head and structural and functional changes in eyes with glaucoma
    Scientific Reports, 10, 729, doi:10.1038/s41598-020-57583-w, 2020.
14. Yoshitaka Ueno, Takeshi Iwase, Kensuke Goto, Ryo Tomita, Eimei Ra, Kentaro Yamamoto and Hiroko Terasaki
    Association of changes of retinal vessels diameter with ocular blood flow in eyes with diabetic retinopathy
    Scientific Reports, 11(1), 1-12, doi:10.1038/s41598-021-84067-2, 2021.
15. Chie Iwase, Takeshi Iwase, Ryo Tomita, Tomohiko Akahori, Eimei Ra, Kentaro Yamamoto and Hiroko Terasaki
    Changes in pulse waveforms in response to intraocular pressure elevation determined by laser speckle flowgraphy in healthy subjects
    BMC Ophthalmology, 21(1), 1-13, doi:10.1186/s12886-021-02070-7, 2021.
16. Ryo Tomita, Takeshi Iwase, Marie Fukami, Kensuke Goto, Eimei Ra and Hiroko Terasaki
    Elevated retinal artery vascular resistance determined by novel visualized technique of laser speckle flowgraphy in branch retinal vein occlusion
    Scientific Reports, 11(1), 1-11, 10.1038/s41598-021-99572-7, 2021.

Department of Ophthalmology, Osaka Medical and Pharmaceutical University

1. S.Kojima, T. Sugiyama, M. Toda, H. Oku, K. Shimizu, O. Ishida, M. Nakajima and I. Azuma
   Effect of nitric oxide on rabbit optic nerve head circulation
   Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995.
2. Okuno T, Sugiyama T, Ikeda T
   Correlation between Heidelberg Retina Flowmeter HRF and laser speckle flowgrafy LSFG
   Invest Ophthalmol Vis Sci 2001;42:S84.
3. Okuno T, Sugiyama T, Kohyama M, Kojima S, Oku H, Ikeda T
   Ocularblood flow changes after dynamic exercise in humans
   Eye. 2006 Jul;20(7):796-800. Epub 2005 Jul 8.
4. Sugiyama T, Oku H, Komori A, et al
   Effect of P2X7 receptor activation on the retinal blood velocity of diabetic rabbits
   Arch Ophthalmol 124:1143-1149,2006
5. Sugiyama T, Kojima S, Ishida O, Ikeda T
   Changes in optic nerve head blood flow induced by the combined therapy of latanoprost and beta blockers.
   Acta Ophthalmol 2008 Dec 2.
6. Sugiyama T, Mashima Y, Yoshioka Y, Oku H, Ikeda T
   Effect of unoprostone on topographic and blood flow changes in the ischemic optic nerve head of rabbits.
   Arch Ophthalmol 127(4):454-9,2009
7. Sugiyama T, Araie M, Riva CE, Schmetterer L, Orgul S
   Use of laser speckle flowgraphy in ocular blood flow research.
   Acta Ophthalmol. :2009 Sep 2.
8. Tetsuya Sugiyama, Maho Shibata, Sumiko Kajiura, Takashi Okuno, Masahiro Tonari, Hidehiro Oku and Tsunehiko Ikeda
   Effects of fasudil, a Rho-associated protein kinase inhibitor, on optic nerve head blood flow in rabbits.
   Investigative ophthalmology & visual science, 52(1): 64-69, 2011.
9. Shibata M, Oku H, Sugiyama T, Kobayashi T, Tsujimoto M, Okuno T, Ikeda T.
   Disruption of Gap Junctions May Be Involved in Impairment of Autoregulation in Optic Nerve Head Blood Flow of Diabetic Rabbits
   IOVS 2011; 52: 2152-2159.
10. Maho Shibata, Tetsuya Sugiyama, Masaaki Hoshiga, Junko Hotchi, Takashi Okuno, Hidehiro Oku, Toshiaki Hanafusa and Tsunehiko Ikeda
    Changes in optic nerve head blood flow, visual function, and retinal histology in hypercholesterolemic rabbits
    Experimental Eye Research, 93(6), 818-824, 2011.
11. Maho Shibata, Tetsuya Sugiyama, Takuji Kurimoto,Hidehiro Oku, Takashi Okuno, Takatoshi Kobayashi ,Tsunehiko Ikeda
    Involvement of Glial Cells in the Autoregulation of Optic Nerve Head Blood Flow in Rabbits
    IOVS 2012; 53: doi: 10.1167/iovs.11-9316
12. Ryohsuke Kohmoto, Tetsuya Sugiyama, Shota Kojima, Mari Ueki and Tsunehiko Ikeda
    Optic Nerve Head Blood Flow Changes Induced by Ripasudil Added to Prostaglandin Analogues in Primary Open Angle Glaucoma
    EC Ophthalmology, 4(6), 640-647, 2017.
13. Teruyo Kida, Josef Flammer, Hidehiro Oku, Katarzyna Konieczka, Seita Morishita, Taeko Horie and Tsunehiko Ikeda
    Vasoactivity of retinal veins: A potential involvement of endothelin-1 (ET-1) in the pathogenesis of retinal vein occlusion (RVO).
    Experimental Eye Research, doi:10.1016/j.exer.2018.07.016, 2018.
14. Teruyo Kida, Josef Flammer, Hidehiro Oku, Katarzyna Konieczka, Seita Morishita, Taeko Horie and Tsunehiko Ikeda
    Vasoactivity of retinal veins
    Data in Brief, doi:10.1016/j.dib.2018.09.070, 2018.
15. Mari Ueki, Tetsuya Sugiyama, Ryohsuke Kohmoto, Shota Kojima, Michiko Maeda, Emika Nemoto, Satoru Tokuoka and Tsunehiko Ikeda
    Blood Flow in the Optic Nerve Head Changes after Disc Hemorrhage in Primary Open Angle Glaucoma
    EC Ophthalmology, 10(3), 230-235, 2019.
16. Ryohsuke Kohmoto, Tetsuya Sugiyama, Mari Ueki, Shota Kojima, Michiko Maeda, Emika Nemoto, Satoru Tokuoka and Tsunehiko Ikeda
    Correlation between laser speckle flowgraphy and optical coherence tomography angiography measurements in normal and glaucomatous eyes
    Clinical Ophthalmology, 13, 1799-1805, 2019.
17. Masashi Mimura, Yuko Nishikawa, Keiko Inagaki, Yohei Sato, Yasushi Fujita and Don O Kikkawa
    Change of intraocular blood flow during treatment for thyroid eye disease
    Taiwan Journal of Ophthalmology, 12(1), 97, doi:10.4103/tjo.tjo_2_22, 2022.

Nakano Eye Clinic

1. Tetsuya Sugiyama
   Basic Technology and Clinical Applications of the Updated Model of Laser Speckle Flowgraphy to Ocular Diseases
   Photonics, 1, no.3, 220-234, 2014. doi:10.3390/photonics1030220
2. Tetsuya Sugiyama, Hajime Nakamura, Emiko Shimizu, Kazuaki Miyamoto and Ryozo Yamada
   Clinical Usefulness of the Measurement of Optic Nerve Head Blood Flow in Myopic Normal-Tension Glaucoma
   International Journal of Ophthalmic Research 2015 June 1(1): 11-18
3. Tetsuya Sugiyama
   Coexisting Normal-Tension Glaucoma and Deficiencies of Folic Acid and Vitamin B6 (Pyridoxal)
   International Journal of Ophthalmology and Clinical Research, 2(4):037, 2015.
4. Tetsuya Sugiyama and Hajime Nakamura
   Increased Short-Term Fluctuation in Optic Nerve Head Blood Flow in a Case of Normal-Tension Glaucoma by the Use of Laser Speckle Flowgraphy.
   Vision 2016, 1, 5.
5. Tetsuya Sugiyama, Emiko Shimizu and Kazuaki Miyamoto
   Ocular Blood Flow Changes in a Case with Nonarterc Ischemic Optic Neuropathy Complicated by Obstructive Sleep Apnea Syndrome
   EC Ophthalmology, 9.6, 361-367, 2018.

Tane Memorial Eye Hospital

1. T.Maeno, R.Tano, M.Sakamoto, N.Onishi, K.Kakurai, T.Yamada, H.Fujii, T.Mano
   Measurement of Retinal Blood Flow Volume by Laser Speckle Flowgraphy Before and After Arteriovenous Sheathotomy for Branch Retinal Vein Occlusion
   ARVO, 2008, (4265/A358)
2. R.Tano, M.Sakamoto, M.Ikeda, S.Sugita, H.Fujii, T.Mano, T.Maeno
   Analysis of Retinal Blood Flow by Laser Speckle Flowgraphy in a Case With Central Retinal Vein Occlusion After Radial Optic Neurotomy
   ARVO, 2008, (4274/A367)

National Cerebral and Cardiovascular Center

1. Junichi Shimamura, Tomohiro Nishinaka, Toshihide Mizuno, Tomonori Tsukiya, Ayako Inatomi, Futoshi Kobayashi, Nobumasa Katagiri, Yoshiaki Takewa, Takashi Nishimura and Eisuke Tatsumi
   Assessment of ocular blood flow in continuous-flow ventricular assist device by laser speckle flowgraphy
   Journal of Artificial Organs, 1-6, doi:10.1007/s10047-021-01265-5, 2021.

Department of Ophthalmology, Kyoto University

1. Yoshimasa Kuroda, Akihito Uji and Nagahisa Yoshimura
   Factors associated with optic nerve head blood flow and color tone: a retrospective observational study.
   Graefe's Archive for Clinical and Experimental Ophthalmology, 1-8, 2016.

Department of Ophthalmology, Saneikai Tsukazaki Hospital

1. Daisuke Nagasato, Yoshinori Mitamura, Kentaro Semba, Kei Akaiwa, Toshihiko Nagasawa, Yuki Yoshizumi, Hitoshi Tabuchi and Yoshiaki Kiuchi
   Correlation between optic nerve head circulation and visual function before and after anti-VEGF therapy for central retinal vein occlusion: prospective, interventional case series
   BMC ophthalmology, 16(1), doi:10.1186/s12886-016-0211-7, 2016.
2. Daisuke Nagasato, Yoshinori Mitamura, Mariko Egawa, Masahiro Kameoka, Toshihiko Nagasawa, Hitoshi Tabuchi, Takamasa Kinoshita, Shozo Sonoda and Taiji Sakamoto
   Changes of choroidal structure and circulation after water drinking test in normal eyes
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi:10.1007/s00417-019-04427-7, 2019.
3. Daisuke Nagasato, Yoshinori Mitamura, Mariko Egawa, Fumiko Murao, Toshihiko Nagasawa, Natsumi Komori, Shozo Sonoda, Taiji Sakamoto and Hitoshi Tabuchi
   Changes in Choroidal Component Ratio and Circulation After Coffee Intake in Healthy Subjects.
   Investigative Ophthalmology & Visual Science, 62(3), 27-27, doi:10.1167/iovs.62.3.27, 2021.

Department of Ophthalmology, Nara Medical University

1. Okamoto M, Matsuura T, Ogata N
   Ocular blood flow before, during, and after vitrectomy determined by laser speckle flowgraphy.
   Ophthalmic Surg Lasers Imaging Retina. 2014 Mar 1;45(2):118-24. doi: 10.3928/23258160-20140306-04.
2. Masahiro Okamoto, Toyoaki Matsuura and Nahoko Ogata
   EFFECTS OF PANRETINAL PHOTOCOAGULATION ON CHOROIDAL THICKNESS AND CHOROIDAL BLOOD FLOW IN PATIENTS WITH SEVERE NONPROLIFERATIVE DIABETIC RETINOPATHY.
   RETINA, 36(4), 805-811, 2016.
3. Masahiro Okamoto, Mariko Yamashita and Nahoko Ogata
   Effects of intravitreal injection of ranibizumab on choroidal structure and blood flow in eyes with diabetic macular edema
   Graefe's Archive for Clinical and Experimental Ophthalmology, 1-8, doi: 10.1007/s00417-018-3939-3, 2018.

Department of Anesthesiology, Nara Medical University

1. Hironobu Hayashi, Masahiro Okamoto, Hideaki Kawanishi, Toyoaki Matsuura, Nobuoki Tabayashi, Shigeki Taniguchi and Masahiko Kawaguchi
   Ocular blood flow measured by laser speckle flowgraphy during aortic arch surgery with antegrade selective cerebral perfusion.
   Journal of Cardiothoracic and Vascular Anesthesia, 2016.
2. Hironobu Hayashi, Masahiro Okamoto, Hideaki Kawanishi, Nobuoki Tabayashi, Toyoaki Matsuura, Shigeki Taniguchi and Masahiko Kawaguchi
   Association between optic nerve head blood flow measured by laser speckle flowgraphy and radial arterial pressure during aortic arch surgery.
   Journal of Cardiothoracic and Vascular Anesthesia, 2017.

Department of Neurosurgery, Nara Medical University

1. Yasushi Motoyama, Hironobu Hayashi, Hideaki Kawanishi, Kohsuke Tsubaki, Tsunenori Takatani, Yoshiaki Takamura, Masashi Kotsugi, Taekyun Kim, Shuichi Yamada, Ichiro Nakagawa, Young-Su Park, Masahiko Kawaguchi and Hiroyuki Nakase
   Ocular blood flow by laser speckle flowgraphy to detect cerebral ischemia during carotid endarterectomy
   Journal of Clinical Monitoring and Computing, doi: 10.1007/s10877-020-00475-1, 2020.

Department of Ophthalmology, Tokushima University

1. Takamasa Kinoshita , Junya Mori, Natsuki Okuda, Hiroko Imaizumi, Masanori Iwasaki, Miho Shimizu, Hirotomo Miyamoto, Kei Akaiwa, Kentaro Semba, Shozo Sonoda, Taiji Sakamoto and Yoshinori Mitamura
   Effects of Exercise on the Structure and Circulation of Choroid in Normal Eyes.
   PLOS ONE, 11(12), e0168336, 2016.

Department of Ophthalmology, Kyushu University

1. Hiroshi Enaida, Kenji Okamoto, Hitoshi Fujii and Tatsuro Ishibashi
   LSFG Findings of Proliferative Diabetic Retinopathy After Intravitreal Injection of Bevacizumab
   Ophthalmic Surgery, Lasers and Imaging 41 Online(): e1-e3, 2010.
2. Masato Akiyama, Yasuhiro Ikeda, Noriko Yoshida, Shoji Notomi, Yusuke Murakami, Toshio Hisatomi, Hiroshi Enaida, Tatsuro Ishibashi
   Therapeutic efficacy of topical unoprostone isopropyl in retins pigmentosa
   Acta Ophthalmologica, DOI: 10.1111/aos.12293, 2013.
3. Yusuke Murakami, Yasuhiro Ikeda, Masato Akiyama, Kota Fujiwara, Noriko Yoshida, Shunji Nakatake, Shoji Notomi, Takahiro Nabeshima, Toshio Hisatomi, Hiroshi Enaida and Tatsuro Ishibashi
   Correlation between macular blood flow and central visual sensvity in retins pigmentosa.
   Acta Ophthalmologica, DOI: 10.1111/aos.12693, 2015.
4. Yusuke Murakami, Jun Funatsu, Shunji Nakatake, Kohta Fujiwara, Takashi Tachibana, Yoshito Koyanagi, Toshio Hisatomi, Shigeo Yoshida, Shozo Sonoda, Taiji Sakamoto, Koh-Hei Sonoda and Yasuhiro Ikeda
   Relations Among Foveal Blood Flow, Retinal-Choroidal Structure, and Visual Function in Retins Pigmentosa
   Investigative Ophthalmology & Visual Science, 59(2), 1134-1143, 2018.

Institute of Health Science, Kyushu University

1. Hayashi N, Ikemura T, Someya N
   Effects of dynamic exercise and its intensity on ocular blood flow in humans.
   Eur J Appl Physiol. 2011
2. Ikemura T, Someya N, Hayashi N
   Autoregulation in the ocular and cerebral arteries during the cold pressor test and handgrip exercise.
   Eur J Appl Physiol.  2011
3. Hideaki Kashima, Naoyuki Hayashi
   Basic Taste Stimuli Elicit Unique Responses in Facial Skin Blood Flow
   PLOS ONE 6(12) 2011: e28236. doi:10.1371/journal.pone.0028236
4. Naoyuki Hayashi, Tsukasa Ikemura, Nami Someya
   Changes in ocular flow induced by hypo- and hypercapnia relate to static visual acuity in humans
   Eye Reports 2011, volume.1:e8, Page.20-24
   
5. Tsukasa Ikemura, Naoyuki Hayashi
   Ocular circulatory responses to exhaustive exercise in humans
   Eur J Appl Physiol. 2012

Department of Ophthalmology, University of Occupational and Environmental Health

1. K.Nagaya, H. Takahashi, H. Fujii
   Optic nerve head microcirculation using laser speckle flowgraphy in patients with normal tension glaucoma
   ARVO, 1999, #1457/B365

Yamana Eye Hospital

1. Y.Yamana, M. Matsuo, N. Konishi and H. Fujii
   Heidelberg Retina Flowmeter and Laser Speckle Flowgraphy System: a comparative evaluation
   Microcirculation Annual, 13, 195-196, 1997.
2. Y.Yamana, M. Matsuo, N. Konishi and H. Fujii
   Peripapillary tissue, retinal vessels and optic nerve head blood flow rates using laser speckle flowgraphy
   20th European Conference on Microcirculation, 219-223, 1998.
3. Y.Yamana, M. Matsuo, K. Goya, N. Konishi and H. Fujii
   Retinal Vessels and Peripapillary Tissue Blood Flow in Diabetes Using Laser Speckle Flowgraphy System: a comparative evaluation
   Microcirculation Annual, 15,117-118, 1999.
4. Y.Yamana, M. Matsuo, Y. Koketu, K. Goya, M. Wakisaka, M. Iwase, M.Yoshinari, N. Konishi, H. Fujii
   Effect Acute Hyperglycemia on Chorio-Retinal Blood Flow in IGT and Diabetes Mellitus
   Microcirculation Annual, 18, 85-86, 2002
5. Y.Yamana, M. Matsuo, Y. Koketsu, K. Goya, M. Yoshinari, N. Konishi, H.Fujii
   Dysregulation of the Postprandial Retinal Blood Flpw in Type 2 Diabetes
   European Society for Microcirculation, 18,95-98, 2002

Department of Ophthalmology, Saga University

1. Hiroshi Enaida, Shinji Nagata, Atsunobu Takeda, Shintaro Nakao, Yasuhiro Ikeda and Tatsuro Ishibashi
   Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy
   Japanese Journal of Ophthalmology, 1-7, doi:10.1007/s10384-016-0472-y, 2016.
2. Hiroaki Sakai, Kosuke Kawata, Jun Masuoka, Tomohisa Nishimura and Hiroshi Enaida
   Diagnosis and clinical course of ocular ischemic syndrome with retinal vascular abnormales due to unilateral ocular artery and internal carotid artery stenosis in a child with neurofibromatosis type 1: a case report
   BMC Ophthalmology, 20(1), 426, doi:10.1186/s12886-020-01670-z, 2020.

Department of Ophthalmology, Nagasaki University

1. Matsumoto Makiko, Suzuma Kiyoshi, Fukazawa Yoshiko, Yamada Yoshihisa, Tsuiki Eiko, Fujikawa Azusa and Kitaoka Takashi
   Retinal blood flow levels measured by Laser Speckle Flowgraphy in patients who received intravitreal bevacizumab injection for macular edema secondary to central retinal vein occlusion.
   Retinal Cases and Brief Reports, 8(1), 60-66, 2014.
2. Y.Yamada, K.Suzuma, M.Matsumoto, E.Tsuiki, A.Fujikawa, T.Harada and T.Kitaoka
   Retinal Blood Flow Correlates to Aqueous Vascular Endothelial Growth Factor in Central Retinal Vein Occlusion.
   RETINA, 35(10), 2037-2042, 2015.
3. Makiko Matsumoto, Kiyoshi Suzuma, Yoshihisa Yamada, Eiko Tsuiki, Azusa Fujikawa and Takashi Kitaoka
   Retinal blood flow after intravitreal bevacizumab is a predictive factor for outcomes of macular edema associated with central retinal vein occlusion.
   Retina, doi:10.1097/IAE.0000000000001531, 2017.
4. Makiko Matsumoto, Kiyoshi Suzuma, Fumito Akiyama, Kanako Yamada, Shiori Harada, Eiko Tsuiki and Takashi Kitaoka
   Retinal Microvascular Resistance Estimated from Waveform Analysis Is Significantly Higher With a Threshold Value in Central Retinal Vein Occlusion
   Translational Vision Science and Technology, 9(11), 4, doi:10.1167/tvst.9.11.4, 2020.
5. Makiko Matsumoto, Kiyoshi Suzuma, Fumito Akiyama, Kanako Yamada, Shiori Harada, Eiko Tsuiki and Takashi Kitaoka
   Retinal Vascular Resistance Significantly Correlates With Visual Acuity After 1 Year of Anti-VEGF Therapy in Central Retinal Vein Occlusion
   Translational Vision Science and Technology, 10(11), 19, doi:10.1167/tvst.10.11.19, 2021.

Department of Ophthalmology, University of Miyazaki

1. Tomoyuki Maekubo, Hideki Chuman, Nobuhisa Nao-i
   Laser speckle flowgraphy for differentiating between nonarterc ischemic optic neuropathy and anterior optic neurs
   Jpn. J. Ophthalmol., May 2013, (doi:10.1007/s10384-013-0246-8)
2. Takako Hidaka, Hideki Chuman and Nobuhisa Nao-I
   Evaluation of optic nerve head blood flow in normal rats and a rodent model of non-arterc ischemic optic neuropathy using laser speckle flowgraphy
   Graefe's Archive for Clinical and Experimental Ophthalmology, 255(10), 1973-1980, 2017.
3. Hideki Chuman, Takako Sugimoto and Nobuhisa Nao-I
   Vasodilatory effect of L-arginine on isolated rabbit and human posterior ciliary arteries in vitro and increased optic disc blood flow in vivo.
   Graefe's Archive for Clinical and Experimental Ophthalmology, 255(12), 2381-2388, 2017.

Devers Eye Institute, Legacy Health System

1. Y.Liang, L. Wang, G. Cull, H. Fujii, J.C. Downs.
   Systemic Blood Pressure Determines the Magnitude of IOP-Induced Blood Flow Change in the Optic Nerve Head of Non-Human Primate
   ARVO, 2008, (3265)
2. Yi Liang, J. Crawford Downs, Brad Fortune, Grant Cull, George A. Cioffi, Lin Wang
   Impact of Systemic Blood Pressure on the Relationship between Intraocular Pressure and Blood Flow in the Optic Nerve Head of Nonhuman Primates
   IOVS, 50:2154-2160, May 2009
3. Yi Liang, Brad Fortune, Grant Cull, George A. Cioffi, Lin Wang
   Quantification of dynamic blood flow autoregulation in Optic nerve head of rhesus monkeys
   Experimental Eye Research, 90, no.2: 203-209, 2010.
4. Lin Wang, Grant A. Cull, Chelsea Piper, Claude F. Burgoyne, Brad Fortune
   Anterior and Posterior Optic Nerve Head Blood Flow in Nonhuman Primate Experimental Glaucoma Model Measured by Laser Speckle Imaging Technique and Microsphere Method
   IOVS, November 20, 2012 IOVS-12-10911
5. Chelsea Piper, Brad Fortune, Grant Cull, George A. Cioffi and Lin Wang
   BASAL BLOOD FLOW AND AUTOREGULATION CHANGES IN THE OPTIC NERVE OF RHESUS MONKEYS WITH IDIOPATHIC BILATERAL OPTIC ATROPHY
   IOVS, January 3, 2013 IOVS-12-9773
6. Grant Cull, Claude F. Burgoyne, Brad Fortune and Lin Wang
   Longitudinal Hemodynamic Changes within the Optic Nerve Head in Experimental Glaucoma
   IOVS, June 4, 2013 IOVS-13-12013
7. Lin Wang, Claude F. Burgoyne, Grant Cull, Simmon Thompson and Brad Fortune
   Static Blood flow Autoregulation in the Optic Nerve Head in Normal and Experimental Glaucoma
   IOVS, January 16, 2014 IOVS-13-13716
8. Jintao Yu, Yi Liang, Simon Thompson, Grant Cull, Lin Wang
   Parametric transfer function analysis and modeling of blood flow autoregulation in the optic nerve head
   Int J Physiol Pathophysiol Pharmacol 2014;6(1):13-22
9. Lin Wang, Grant Cull, Claude F. Burgoyne, Simon Thompson and Brad Fortune
   Longitudinal Alterations in the Dynamic Autoregulation of Optic Nerve Head Blood Flow Revealed in Experimental Glaucoma
   IOVS, May 8, 2014 IOVS-14-14020. doi:10.1167/iovs.14-14020
10. Lin Wang, Grant A. Cull and Brad Fortune
    Optic Nerve Head Blood Flow Response to Reduced Ocular Perfusion Pressure by Alteration of Either the Blood Pressure or Intraocular Pressure
    Current Eye Research, Posted online on June 9, 2014. (doi:10.3109/02713683.2014.924146)
11. Grant Cull, Reinhard Told, Claude F. Burgoyne, Simon Thompson, Brad Fortune and Lin Wang
    Compromised Optic Nerve Blood Flow and Autoregulation Secondary to Neural DegenerationHemodynamics Secondary to Optic Nerve Degeneration.
    IOVS, 56(12), 7286-7292, 2015.
12. Stuart K. Gardiner, Grant Cull, Brad Fortune and Lin Wang
    Increased Optic Nerve Head Capillary Blood Flow in Early Primary Open-Angle Glaucoma
    IOVS, 60(8), 3110-3118, doi:10.1167/iovs.19-27389, 2019.
13. Stuart Keith Gardiner, Grant Cull, Juan Reynaud, Steven L Mansberger, Brad Fortune and Lin Wang
    The relation between blood flow within the remaining peripapillary vasculature and functional progression in glaucoma
    Investigative Ophthalmology & Visual Science, 61(7), 620, 2020.

Department of Veterinary Medicine and Surgery, University of Missouri

1. Shyam S. Chaurasia, Rayne R. Lim, Bhav H. Parikh, Yeo Sia Wey, Bo Bo Tun, Tien Yin Wong, Chi D. Luu, Rupesh Agrawal, Arkasubhra Ghosh, Alessandra Mortellaro, Elizabeth Rackoczy, Rajiv R. Mohan and Veluchamy A. Barathi
   The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
   Scientific reports, 8(1), 2847, doi:10.1038/s41598-018-21198-z, 2018.

Department of Ophthalmology and Visual Sciences, University of Iowa

1. Sophia M Chung, Zaidoon Al-Share, Matthew J. Thurtell, Ryuya Hashimoto and Randy Kardon
   Blood Flow in the Optic Nerve and Peripapillary Choroid Correlate Over Time in NAION
   Investigative Ophthalmology & Visual Science, 61(7), 804, 2020.
2. Ryuya Hashimoto, Zaidoon Al-Share, Nitsan Duvdevan-Strier, Jan M Full, Julie Nellis and Randy Kardon
   Autoregulation of Blood Flow in the Human Retina, Optic Nerve, and Choroid in Response to Acute Decrease in Intraocular Pressure Using Novel Vacuum Goggles
   Investigative Ophthalmology & Visual Science, 61(7), 1735, 2020.
3. Zaidoon Y Alshare, Ryuya Hashimoto and Randy Kardon
   Reduced Blood Flow in the Choroidal Watershed and Parapapillary Hypoperfusion Zones and Relation to Optic Disc Blood Flow
   Investigative Ophthalmology & Visual Science, 61(7), 1744, 2020.
4. Michelle R. Tamplin, Kimberly A. Broadhurst, Anthony H. Vitale, Ryuya Hashimoto, Randy H. Kardon and Isabella M. Grumbach
   Longitudinal Testing of Retinal Blood Flow in a Mouse Model of Hypertension by Laser Speckle Flowgraphy
   Translational vision science & technology, 10(2), 16-16, doi:10.1167/tvst.10.2.16, 2021.
5. Jui-Kai Wang, Michelle R. Tamplin, Mona K. Garvin, Isabella M. Grumbach and Randy H. Kardon
   A superpixel-histogram method to analyze retinal, optic nerve, and choroidal blood flow using laser speckle flowgraphy
   Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging, 1203622, doi:10.1117/12.2611850, 2022.

Department of Health and Human Physiology, University of Iowa

1. Seth W. Holwerda, Randy H. Kardon, Ryuya Hashimoto, Jan M. Full, Julie K. Nellis, Lyndsey E. DuBose, Jess G. Fiedorowicz, and Gary L. Pierce
   Aortic stiffness is associated with changes in retinal arteriole flow pulsatility mediated by local vasodilation in healthy young/middle-age adults
   Journal of Applied Physiology, doi: 10.1152/japplphysiol.00252.2020, 2020.

Department of Radiation Oncology, University of Iowa

1. Michelle R.Tamplin, Kimberly A.Broadhurst, Anthony H.Vitale, Ryuya Hashimoto, Randy H.Kardon and Isabella M.Grumbach
   Measuring hyperemic response to light flicker stimulus using continuous laser speckle flowgraphy in mice
   Experimental Eye Research, 216, 108952, doi:10.1016/j.exer.2022.108952, 2022.

Division of Ophthalmology, Beth Israel Deaconess Medical Center, Harvard Medical School

1. Rachelle Koch, Brendan Seto, Keiko Yamada, Purva Atreay, Colin A. Lemire, Nina Hazra and Jorge G. Arroyo
   Relative Retinal Blood Flow: A Novel and Informative Measure of Unilateral Retinal Vein Occlusion Severity
   Translational Vision Science & Technology, 10(3), 15-15, doi:10.1167/tvst.10.3.15, 2021.
2. Shashvat Chandrakant Purohit, Colin A Lemire, Brendan Seto, Keiko Yamada and Jorge G Arroyo
   Relative Retinal Blood Flow in Patients with Central Retinal Artery Occlusions
   Investigative Ophthalmology and Visual Science, 62(8), 3197, 2021 ARVO Annual Meeting abstract, 2021.

Department of Clinical Pharmacology, Medical University of Vienna

1. P.A. Wozniak, N. Luft, G. Aschinger, K. Fondi, A.M. Bata, K.J. Witkowska, D. Schmidl, R.M. Werkmeister, M. Bolz, G. Garh?fer and L. Schmetterer
   The assessment of ocular blood flow with laser speckle flowgraphy in healthy caucasian.
   Acta Ophthalmologica, 2016, 94.S256. doi: 10.1111/j.1755-3768.2016.0391
2. Nikolaus Luft, Piotr A. Wozniak, Gerold C. Aschinger, Klemens Fondi, Ahmed M. Bata, René M. Werkmeister, Doreen Schmidl, Katarzyna J. Witkowska, Matthias Bolz, Gerhard Garh?fer and Leopold Schmetterer
   Measurements of Retinal Perfusion Using Laser Speckle Flowgraphy and Doppler Optical Coherence Tomography
   IOVS, 57(13), 5417-5425, 2016.
3. Nikolaus Luft, Piotr A. Wozniak, Gerold C. Aschinger, Klemens Fondi, Ahmed M. Bata, René M. Werkmeister, Doreen Schmidl, Katarzyna J. Witkowska, Matthias Bolz, Gerhard Garh?fer and Leopold Schmetterer
   Ocular Blood Flow Measurements in Healthy White Subjects Using Laser Speckle Flowgraphy
   PLOS ONE, 11(12), e0168190, 2016.
4. D.Schmidl, K.Witkowska, N.Luft, M.Bolz, K.Fondi, A.Bata, P.Wozniak, R.Werkmeister, G.Garhofer and L.Schmetterer
   Assessment of retinal blood flow using Laser Speckle Flowgraphy
   Acta Ophthalmologica, 95.S259, doi: 10.1111/j.1755-3768.2017.01145, 2017.
5. Katarzyna J. Witkowska, Ahmed M. Bata, Giacomo Calzetti, Nikolaus Luft, Klemens Fondi, Piotr A. Wozniak, Doreen Schmidl, Matthias Bolz, Alina Popa-Cherecheanu, René M. Werkmeister, Gerhard Garh?fer and Leopold Schmetterer
   Optic nerve head and retinal blood flow regulation during isometric exercise as assessed with laser speckle flowgraphy
   PLOS ONE, 12(9), e0184772, doi: 10.1371/journal.pone.0184772, 2017.
6. Giacomo Calzetti, Klemens Fondi, Ahmed M Bata, Nikolaus Luft, Piotr A Wozniak, Katarzyna J Witkowska, Matthias Bolz, Alina Popa-Cherecheanu, René M Werkmeister, Doreen Schmidl, Gerhard Garh?fer and Leopold Schmetterer
   Assessment of choroidal blood flow using laser speckle flowgraphy
   Brsh Journal of Ophthalmology, bjophthalmol-2017-311750, doi: 10.1136/bjophthalmol-2017-311750, 2018.
7. Fondi K, Bata AM, Luft N, Witkowska KJ, Werkmeister RM, Schmidl D, Bolz M, Schmetterer L and Garh?fer G
   Evaluation of flicker induced hyperemia in the retina and optic nerve head measured by Laser Speckle Flowgraphy.
   PLOS ONE, 13(11), e0207525, doi:10.1371/journal.pone.0207525, 2018.

Department for Ophthalmology, Kepler University Hospital

1. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
   Laser speckle flowgraphy derived characteristics of optic nerve head perfusion in normal tension glaucoma and healthy individuals: a Pilot study.
   Scientific Reports, 8(1), 5343, doi:10.1038/s41598-018-23149-0, 2018.
2. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
   Short-term effect on the ocular circulation inducedby unilateral intravitreal injection of aflibercept inage-related maculopathy
   Acta Ophthalmologica, doi:10.1111/aos.14098, 2019.
3. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
   Differences in Optic Nerve Head Blood Flow Regulation in Normal Tension Glaucoma Patients and Healthy Controls as Assessed with Laser Speckle Flowgraphy During the Water Drinking Test
   Journal of Glaucoma, doi:10.1097/IJG.0000000000001258, 2019.
4. Anna Sophie Mursch-Edlmayr, Nikolaus Luft, Dominika Podkowinski, Michael Ring, Leopold Schmetterer and Matthias Bolz
   Effects of three intravitreal injections of aflibercept on the ocular circulation in eyes with age-related maculopathy
   Brsh Journal of Ophthalmology, doi:10.1136/bjophthalmol-2019-313919, 2019.
5. A.S. Mursch-Edlmayr, L. Pickl, G. Calzetti, K. Waser, J. Wendelstein, S. Beka, V. Aranha dos Santos, N. Luft, L. Schmetterer and M. Bolz
   Comparison of neurovascular coupling between normal tension glaucoma patients and healthy individuals with Laser Speckle Flowgraphy.
   Current eye research, doi: 10.1080/02713683.2020.1752390, 2020.

Ophthalmology Unit, University Hospital of Parma

1. Giacomo Calzetti, Paolo Mora, Stefania Favilla, Giorgia Ottonelli, Giulia Devincenzi, Arturo Carta, Salvatore Tedesco, Anna Mursch-Edlmayr, Gerhard Garh?fer, Stefano Gandolfi, Leopold Schmetterer
   Assessment of Choroidal Neovascularization Perfusion: A Pilot Study With Laser Speckle Flowgraphy
   Translational Vision Science & Technology, 9(5), 9, doi: 10.1167/tvst.9.5.9, 2020.
2. Giacomo Calzetti, Federica Angella, Alice Galli, Giada Marcantoni, Alessandro Romani, Mariabeatrice Simonelli, Paolo Mora, Stefano A Gandolfi, Leopold Schmetterer and Arturo Carta
   Longitudinal changes in optic nerve head perfusion in non-arterc anterior ischemic optic neuropathy
   Investigative Ophthalmology & Visual Science, 61(7), 3951, 2020.
3. Giacomo Calzetti, Paolo Mora, Alessandro Romani, Giorgia Ottonelli, Alessandra Pareti, Stefano Gandolfi, Leopold Schmetterer and Arturo Carta
   Optic nerve head and peripapillary perfusion as assessed with laser speckle flowgraphy in non-arterc anterior ischaemic optic neuropathy
   Acta Ophthalmologica, 99(3), e445-e446, doi:10.1111/aos.14555, 2020.
4. Giacomo Calzetti, Anna Sophie Mursch-Edlmayr, Ahmed M. Bata, Nicola Ungaro, Paolo Mora, Jacqueline Chua, Doreen Schmidl, Matthias Bolz, Gerhard Garh?fer, Stefano Gandolfi, Leopold Schmetterer and Damon Wong
   Measuring optic nerve head perfusion to monitor glaucoma: a study on structure-function relationships using laser speckle flowgraphy.
   Acta Ophthalmologica, doi:10.1111/aos.14862, 2021.
5. Giacomo Calzetti, Paolo Mora, Enrico Borrelli, Riccardo Sacconi, Guido Ricciotti, Arturo Carta, Stefano Gandolfi and Giuseppe Querques
   Short-term changes in retinal and choroidal relative flow volume after anti-VEGF treatment for neovascular age-related macular degeneration
   Scientific Reports, 11(1), 1-7, 23723, doi:10.1038/s41598-021-03179-x, 2021.

Institute of Molecular and Clinical Ophthalmology Basel

1. Giacomo Calzetti, Chiara La Morgia, Marco Cattaneo, Arturo Carta, Francesca Bosello, Giulia Amore, Michele Carbonelli, Maria Lucia Cascavilla, Stefano Gandolfi, Valerio Carelli, Leopold Schmetterer, Hendrik P. N. Scholl and Piero Barboni
   Longitudinal Study of Optic Disk Perfusion and Retinal Structure in Leber's Hereditary Optic Neuropathy
   Investigative Ophthalmology and Visual Science, 63(1), 43, doi:10.1167/iovs.63.1.43, 2022.

Ophthalmology Clinic, Department of Medicine and Science of Ageing, University "G. d' Annunzio"

1. Lisa Toto, Federica Evangelista, Pasquale Viggiano, Emanuele Erroi, Giada D'Onofrio, Daniele Libertini, Annamaria Porreca, Rossella D'Aloisio, Parravano Mariacristina, Luca Di Antonio, Marta Di Nicola and Rodolfo Mastropasqua
   Changes in Ocular Blood Flow after Ranibizumab IntravitrealInjection for Diabetic Macular Edema Measured Using LaserSpeckle Flowgraphy
   BioMed Research International, 2020, 9496242, doi:10.1155/2020/9496242, 2020.

Department of Ophthalmology, Rigshospitalet

1. Jakob W?gstr?m, Lasse Malmqvist and Steffen Hamann
   Optic Nerve Head Blood Flow Analysis in Patients with Optic Disc Drusen Using Laser Speckle Flowgraphy
   Neuro-Ophthalmology, doi:10.1080/01658107.2020.1795689, 2020.

Ophthalmology, University Medical Center Groningen

1. Konstantinos Pappelis, Lars Choritz and Nomdo Jansonius
   Microcirculatory model predicts blood flow and autoregulation range in the human retina: in vivo investigation with Laser Speckle Flowgraphy
   American Journal of Physiology-Heart and Circulatory Physiology, doi:10.1152/ajpheart.00404.2020, 2020.

Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital

1. X. Wei, A. Barathi, B.B. Sai, P.K. Balne, N. Khandelwal and R. Agrawal
   Assessment of chorioretinal blood flow and vessel diameter by laser speckle flowgraphy in three animal models
   Acta Ophthalmologica, 2016, 94.S256. doi: 10.1111/j.1755-3768.2016.0566

Univers Teknologi PETRONAS

1. M. S. Bhatti, W. Rasheed, T. B. Tang and A. Laude
   Investigating eye-strain due to prolonged exposure to low resolution multimedia using LSFG
   2016 6th International Conference on Intelligent and Advanced Systems (ICIAS), doi:10.1109/ICIAS.2016.7824096, 2016.
2. Mehwish Saba Bhatti, Tong Boon Tang and Augustinus Laude
   Effects of water drinking test on ocular blood flow waveform parameters: A laser speckle flowgraphy study
   PLoS ONE 12(7): e0181512. doi:10.1371/journal.pone.0181512, 2017.
3. Mehwish Saba Bhatti, Tong Boon Tang and Hui Cheng Chen
   Ocular Blood Flow in Rabbits under Deep Anesthesia: A Real-Time Measurement Technique and Its Application in Characterizing Retinal Ischemia
   Scientific Reports, 8(1), 5713, doi:10.1038/s41598-018-24141-4, 2018.
4. Aishah Ismail, Mehwish S. Bhatti, Ibrahima Faye, Cheng Kai Lu, Augustinus Laude and Tong Boon Tang
   Pulse waveform analysis on temporal changes in ocular blood flow due to caffeine intake: a comparative study between habitual and non-habitual groups
   Graefe's Archive for Clinical and Experimental Ophthalmology, doi: 10.1007/s00417-018-4030-9, 2018.
5. Aishah Ismail, Tong Boon Tang, Faye Ibrahima and Chen Hui Cheng
   Animal Model - Investigation of Laser Speckle Flowgraphy for Early Carotid Artery Stenosis Detection
   2018 International Conference on Intelligent and Advanced System (ICIAS), doi:10.1109/ICIAS.2018.8540566, 2018.
6. Aishah Ismail, Hui Cheng Chen, Ibrahima Faye and Tong Boon Tang
   Longitudinal effects of common carotid artery stenosis on ocular hemodynamics assessed using laser speckle flowgraphy in a rabbit model
   Scientific Reports, 10(1), 15829, doi:10.1038/s41598-020-72556-9, 2020.

Taipei Medical University

1. Yen-Ju Chan, Po-Lin Liao, Chi-Hao Tsai, Yu-Wen Cheng, Fan-Li Lin, Jau-Der Ho, Ching-Yi Chen and Ching-Hao Li
   Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
   Particle and fibre toxicology, 18(1), 1-16, doi:10.1186/s12989-020-00395-7, 2021.

Department of Ophthalmology, Chang Gung Memorial Hospital

1. Margaret Ming-Chih Ho, Yueh-Ju Tsai, Yen-Chang Chu and Yi-Lin Liao
   Evaluation of Microcirculation in Optic Nerve Head Using Laser Speckle Flowgraphy in Active Thyroid Eye Disease
   BioMed Research International, doi:10.1155/2022/9115270, 2022.

Department of Ophthalmology, College of Medicine, King Saud University

1. Ahmed M. Abu El-Asrar, Waleed Alsarhani, Abdullah Alzubaidi and Priscilla W. Gikandi
   Effect of immunosuppressive therapy on ocular blood flow in inal-onset acute uves associated with Vogt–Koyanagi–Harada disease.
   Acta Ophthalmologica, doi:10.1111/aos.14842, 2021.
2. Ahmed M. Abu El-Asrar, Abdulrahman F. AlBloushi, Priscilla W. Gikandi, Abdullah Alzubaidi and Einar Stefánsson
   Changes in ocular blood flow and retinal oxygen metabolism during immunosuppressive therapy for inal-onset acute uves associated with Vogt–Koyanagi–Harada disease
   Acta Ophthalmologica, doi:10.1111/aos.15122, 2022.

Senju Pharmaceutical Co.,Ltd

1. Hiroaki Takahashi, Tetsuya Sugiyama, Hideki Tokushige, Takatoshi Maeno, Toru Nakazawa, Tsunehiko Ikeda, Makoto Araie
   Comparison of CCD-equipped laser speckle flowgraphy with hydrogen gas clearance method in the measurement of optic nerve head microcirculation in rabbits
   Experimental Eye Research(2012), http://dx.doi.org/10.1016/j.exer.2012.12.003

Department of Computer Science and Electronics, Kyushu Institute of Technology

1. H.Fujii
   Visualization of retinal blood flow by laser speckle flowgraphy
   Med. Bio. Eng. & Comp., 32, no.3, 302-304, 1994.
2. Naoki Konishi, Hitoshi Fujii
   Real-time Visualization of retinal microcirculation by laser flowgraphy
   Optical Enginnering, 34, no.3,753-757, 1995.
3. H. Fujii, N. Konishi, K. Okamoto and Y. Tsuchihashi
   Evaluation of Retinal Microcirculation by Real-Time Laser Flowgraphy
   Proc. 2nd Internet Ocular Blood Circulation Symposium, 1995.
4. Hitoshi Fujii and Naoki Konishi
   Visualization of Blood Flow Using Laser Speckle Method
   Proceedings of 18th Annual International Conference, No.688 1996.
5. Hitoshi Fujii Yoshihiko Tsuchihashi and Naoki Konishi
   Evaluation of Retinal Microcirculation by Real-Time Laser Flowgraphy(II)
   Proc. 3rd Internet World Congress on Biomedical Sciences, 1996
6. Hitoshi Fujii
   Laser Speckle Blood Flowgraphy Medical Diagnostic Techniques and Procedures, Megha Singh et.al. Ed.,
   216-224 (Narosa Publishing House, New Delhi, London, 1999)
7. Naoki Konishi, Yoshinori Tokimoto, Kazuhiro Kohra and Hitoshi Fujii
   New Laser Speckle Flowgraphy System Using CCD Camera
   Optical Review, 9, No.4, 163-169, 2002
8. Min-Chul Lee, Naoki Konishi and Hitoshi Fujii
   Blood Flow Analyses of Skin Tissue Under the Sacrum Using Laser Speckle Flowgraphy
   Optical Review, 10, No. 6, 562-566, 2003